A Proximity biotinylation assay with a host protein bait reveals multiple factors modulating enterovirus replication
As ultimate parasites, viruses depend on host factors for every step of their life cycle. On the
other hand, cells evolved multiple mechanisms of detecting and interfering with viral …
other hand, cells evolved multiple mechanisms of detecting and interfering with viral …
Multifunctionality of structural proteins in the enterovirus life cycle
X Wen, D Sun, J Guo, F Elgner, M Wang… - Future …, 2019 - Taylor & Francis
Members of the genus Enterovirus have a significant effect on human health, especially in
infants and children. Since the viral genome has limited coding capacity, Enteroviruses …
infants and children. Since the viral genome has limited coding capacity, Enteroviruses …
Origins of enterovirus replication organelles established by whole-cell electron microscopy
CE Melia, CJ Peddie, AWM de Jong, EJ Snijder… - MBio, 2019 - Am Soc Microbiol
Enterovirus genome replication occurs at virus-induced structures derived from cellular
membranes and lipids. However, the origin of these replication organelles (ROs) remains …
membranes and lipids. However, the origin of these replication organelles (ROs) remains …
Recent advances from studies on the role of structural proteins in enterovirus infection
X Wen, A Cheng, M Wang, R Jia, D Zhu… - Future …, 2015 - Taylor & Francis
Enteroviruses are a large group of small nonenveloped viruses that cause common and
debilitating illnesses affecting humans and animals worldwide. The capsid composed by …
debilitating illnesses affecting humans and animals worldwide. The capsid composed by …
Illuminating the sites of enterovirus replication in living cells by using a split-GFP-tagged viral protein
HM Van der Schaar, CE Melia, JAC Van Bruggen… - MSphere, 2016 - Am Soc Microbiol
Like all other positive-strand RNA viruses, enteroviruses generate new organelles
(replication organelles [ROs]) with a unique protein and lipid composition on which they …
(replication organelles [ROs]) with a unique protein and lipid composition on which they …
The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication
F Téoulé, C Brisac, I Pelletier, PO Vidalain… - Journal of …, 2013 - Am Soc Microbiol
We have shown that the circulating vaccine-derived polioviruses responsible for
poliomyelitis outbreaks in Madagascar have recombinant genomes composed of sequences …
poliomyelitis outbreaks in Madagascar have recombinant genomes composed of sequences …
Generation of unique poliovirus RNA replication organelles
AL Richards, JAP Soares-Martins, GT Riddell… - MBio, 2014 - Am Soc Microbiol
Poliovirus (PV), a model for interactions of picornaviruses with host cells, replicates its
genomic RNA in association with cellular membranes. The origin of PV replication …
genomic RNA in association with cellular membranes. The origin of PV replication …
Enterovirus replication organelles and inhibitors of their formation
X Li, M Wang, A Cheng, X Wen, X Ou, S Mao… - Frontiers in …, 2020 - frontiersin.org
Enteroviral replication reorganizes the cellular membrane. Upon infection, viral proteins and
hijacked host factors generate unique structures called replication organelles (ROs) to …
hijacked host factors generate unique structures called replication organelles (ROs) to …
The life cycle of non-polio enteroviruses and how to target it
J Baggen, HJ Thibaut, JRPM Strating… - Nature Reviews …, 2018 - nature.com
The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus,
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …
Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts
R Chandler-Bostock, CP Mata, RJ Bingham… - PLoS …, 2020 - journals.plos.org
Picornaviruses are important viral pathogens, but despite extensive study, the assembly
process of their infectious virions is still incompletely understood, preventing the …
process of their infectious virions is still incompletely understood, preventing the …