A Proximity biotinylation assay with a host protein bait reveals multiple factors modulating enterovirus replication

S Moghimi, EG Viktorova, S Gabaglio, A Zimina… - PLoS …, 2022 - journals.plos.org
As ultimate parasites, viruses depend on host factors for every step of their life cycle. On the
other hand, cells evolved multiple mechanisms of detecting and interfering with viral …

Multifunctionality of structural proteins in the enterovirus life cycle

X Wen, D Sun, J Guo, F Elgner, M Wang… - Future …, 2019 - Taylor & Francis
Members of the genus Enterovirus have a significant effect on human health, especially in
infants and children. Since the viral genome has limited coding capacity, Enteroviruses …

Origins of enterovirus replication organelles established by whole-cell electron microscopy

CE Melia, CJ Peddie, AWM de Jong, EJ Snijder… - MBio, 2019 - Am Soc Microbiol
Enterovirus genome replication occurs at virus-induced structures derived from cellular
membranes and lipids. However, the origin of these replication organelles (ROs) remains …

Recent advances from studies on the role of structural proteins in enterovirus infection

X Wen, A Cheng, M Wang, R Jia, D Zhu… - Future …, 2015 - Taylor & Francis
Enteroviruses are a large group of small nonenveloped viruses that cause common and
debilitating illnesses affecting humans and animals worldwide. The capsid composed by …

Illuminating the sites of enterovirus replication in living cells by using a split-GFP-tagged viral protein

HM Van der Schaar, CE Melia, JAC Van Bruggen… - MSphere, 2016 - Am Soc Microbiol
Like all other positive-strand RNA viruses, enteroviruses generate new organelles
(replication organelles [ROs]) with a unique protein and lipid composition on which they …

The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication

F Téoulé, C Brisac, I Pelletier, PO Vidalain… - Journal of …, 2013 - Am Soc Microbiol
We have shown that the circulating vaccine-derived polioviruses responsible for
poliomyelitis outbreaks in Madagascar have recombinant genomes composed of sequences …

Generation of unique poliovirus RNA replication organelles

AL Richards, JAP Soares-Martins, GT Riddell… - MBio, 2014 - Am Soc Microbiol
Poliovirus (PV), a model for interactions of picornaviruses with host cells, replicates its
genomic RNA in association with cellular membranes. The origin of PV replication …

Enterovirus replication organelles and inhibitors of their formation

X Li, M Wang, A Cheng, X Wen, X Ou, S Mao… - Frontiers in …, 2020 - frontiersin.org
Enteroviral replication reorganizes the cellular membrane. Upon infection, viral proteins and
hijacked host factors generate unique structures called replication organelles (ROs) to …

The life cycle of non-polio enteroviruses and how to target it

J Baggen, HJ Thibaut, JRPM Strating… - Nature Reviews …, 2018 - nature.com
The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus,
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …

Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts

R Chandler-Bostock, CP Mata, RJ Bingham… - PLoS …, 2020 - journals.plos.org
Picornaviruses are important viral pathogens, but despite extensive study, the assembly
process of their infectious virions is still incompletely understood, preventing the …