Drug resistance, evasion of cell death and metastasis are factors that contribute to the low
cure rate and disease-free survival in osteosarcomas (OS). In this study, we demonstrated …

The cytotoxic activity against human carcinogenic cells of five compounds, three of them
containing palladium (II) and one containing platinum (II) was evaluated for the first time …

This work reports the half maximal inhibitory concentrations, IC50, for conventional anti‐
cancer drug oxaliplatin (OXA) and potential new drugs Pt2Cl2Spm (Pt2Spm) and …

With the aim of overcoming the well-known limitations of platinum-based antineoplastic
drugs, recent efforts have focused on the development of new anticancer agents containing …

Even though platinum (II/IV) complexes are found to be very active as anticancer agents,
they have many well-known limitations. These drawbacks reflect through severe side-effects …

Effective treatment methods for human leukemia are under development, but so far none of
them have been found to be completely satisfactory. It was recently reported that palladium …

Current precious-metal-containing anticancer agents are mostly chelated with N-containing
ligands and function by interacting with DNA. In the present study, Pd (acac) 2, a Pd (II) …

Our search of new organopalladium compounds able to promote an effective
antiproliferative action towards ovarian cancer cells continues. In this paper we have …

New palladium compounds [Pd {(1S, 4R)-NOH^ NH (R)} Cl2](R= Ph 1a or Bn 1b),[Pd {(1S,
4R)-NOH^ NH (R)}{(1S, 4R)-NO^ NH (R)}][Cl](R= Ph 2a or Bn 2b) and corresponding [Pd …

This review deals with the most important results published on the structures, reactivity and
biomedical applications of palladium (II) complexes in the cancer therapy in the last five …