[HTML][HTML] Mesenchymal stromal cells: putative microenvironmental modulators become cell therapy

M Krampera, K Le Blanc - Cell stem cell, 2021 - cell.com
An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …

Mechanisms of immune modulation by mesenchymal stromal cells and clinical translation

J Stagg, J Galipeau - Current molecular medicine, 2013 - ingentaconnect.com
Cell therapy with mesenchymal stromal cells (MSCs) is the focus of intensive investigation.
Several clinical trials, including large-scale placebo-controlled phase III clinical trials, are …

The influence of macrophages on mesenchymal stromal cell therapy: passive or aggressive agents?

F Carty, BP Mahon, K English - Clinical & Experimental …, 2017 - academic.oup.com
Mesenchymal stromal cells (MSC) have emerged as promising cell therapies for multiple
conditions based on demonstrations of their potent immunomodulatory and regenerative …

Safety and efficacy of mesenchymal stromal cell therapy in autoimmune disorders

ME Bernardo, WE Fibbe - Annals of the New York Academy of …, 2012 - Wiley Online Library
Mesenchymal stromal cells (MSCs) are being employed in clinical trials to facilitate
engraftment and to treat steroid‐resistant acute graft‐versus‐host disease after …

[HTML][HTML] Mesenchymal stromal cells for the treatment of graft versus host disease

K Kelly, JEJ Rasko - Frontiers in immunology, 2021 - frontiersin.org
Graft versus host disease (GvHD) is a life-threating complication of allogeneic hematopoietic
stem cell transplantation, which is initially treated with high dose corticosteroids …

Treatment of graft-versus-host-disease with mesenchymal stromal cells

P Kebriaei, S Robinson - Cytotherapy, 2011 - Elsevier
Mesenchymal stromal cells (MSC) are a population of phenotypically heterogeneous cells
that can be isolated from many readily accessible tissues, including bone marrow, umbilical …

[HTML][HTML] Clinical-scale expansion of mesenchymal stromal cells: a large banking experience

C Lechanteur, A Briquet, O Giet, O Delloye… - Journal of Translational …, 2016 - Springer
Background Mesenchymal stromal cells (MSC) are largely investigated in clinical trials
aiming to control inappropriate immune reactions (GVHD, Crohn's disease, solid organ …

[HTML][HTML] Current perspectives on mesenchymal stromal cell therapy for graft versus host disease

N Kadri, S Amu, E Iacobaeus, E Boberg… - Cellular & Molecular …, 2023 - nature.com
Graft versus host disease (GvHD) is the clinical condition in which bone marrow-derived
mesenchymal stromal cells (MSCs) have been most frequently studied. In this review, we …

[HTML][HTML] Mesenchymal stromal cells: facilitators of successful transplantation?

K English, A French, KJ Wood - Cell stem cell, 2010 - cell.com
Mesenchymal stromal/stem cells (MSCs) possess immunomodulatory and reparative
properties. Through specific interactions with immune cells that participate in both innate …

Concise review: adult mesenchymal stromal cell therapy for inflammatory diseases: how well are we joining the dots?

MD Griffin, SJ Elliman, E Cahill, K English… - Stem …, 2013 - academic.oup.com
Mesenchymal stromal (stem) cells (MSCs) continue to be a strong area of focus for
academic-and industry-based researchers who share the goal of expanding their …