Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine

E Cernuda-Morollón, D Larrosa, C Ramón, J Vega… - Neurology, 2013 - AAN Enterprises
Objective: To determine calcitonin gene-related peptide (CGRP) levels outside migraine
attacks in peripheral blood as a potential biomarker for chronic migraine (CM). Methods …

[HTML][HTML] Feasibility of serum CGRP measurement as a biomarker of chronic migraine: a critical reappraisal

MJ Lee, SY Lee, S Cho, ES Kang… - The journal of headache …, 2018 - Springer
Background Calcitonin gene-related peptide (CGRP) has been reported as elevated in
chronic migraine. We aimed to validate the role of interictal serum CGRP concentration in …

Plasma levels of calcitonin gene-related peptide in chronic tension-type headache

M Ashina, L Bendtsen, R Jensen, S Schifter… - Neurology, 2000 - AAN Enterprises
Background: Calcitonin gene-related peptide (CGRP) is involved in the pathophysiology of
migraine and cluster headache. Whether CGRP has any role in chronic tension-type …

Serum Alpha and Beta‐CGRP Levels in Chronic Migraine Patients Before and After Monoclonal Antibodies Against CGRP or its Receptor

G Gárate, V González‐Quintanilla… - Annals of …, 2023 - Wiley Online Library
Objective The objective of this study was to analyze the evolution of alpha and beta‐CGRP
circulating levels throughout CGRP monoclonal antibodies (mAbs) treatment in patients with …

CGRP may play a causative role in migraine

LH Lassen, PA Haderslev, VB Jacobsen… - …, 2002 - journals.sagepub.com
Calcitonin gene-related peptide (CGRP) has been detected in increased amounts in
external jugular venous blood during migraine attacks. However, it is unknown whether this …

No increase of calcitonin gene–related peptide in jugular blood during migraine

JF Tvedskov, K Lipka, M Ashina… - Annals of Neurology …, 2005 - Wiley Online Library
Increased calcitonin gene–related peptide (CGRP) in external jugular venous blood during
migraine attack is one of the most cited findings in the headache literature. The finding has …

Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura

JM Hansen, AW Hauge, J Olesen, M Ashina - Cephalalgia, 2010 - journals.sagepub.com
Introduction: Calcitonin gene-related peptide (CGRP) is a key molecule in migraine
pathogenesis. Intravenous CGRP infusion triggers delayed migraine-like attacks in patients …

Evidence for increased plasma levels of calcitonin gene-related peptide in migraine outside of attacks

M Ashina, L Bendtsen, R Jensen, S Schifter, J Olesen - Pain, 2000 - journals.lww.com
Although calcitonin gene-related peptide (CGRP) has been shown to be elevated in jugular
venous blood of adult migraineurs during acute migraine attacks, it remains unknown …

Salivary CGRP can monitor the different migraine phases: CGRP (in) dependent attacks

A Alpuente, VJ Gallardo, L Asskour, E Caronna… - …, 2022 - journals.sagepub.com
Background CGRP plays a key role in the transmission and modulation of nociceptive
signals and is a critical component in the pathogenesis of migraine. Objective To assess …

Calcitonin gene-related peptide levels in tear fluid are elevated in migraine patients compared to healthy controls

K Kamm, A Straube, R Ruscheweyh - Cephalalgia, 2019 - journals.sagepub.com
Background Calcitonin gene-related peptide (CGRP) released from trigeminal nerve fibres
indicates trigeminal activation and has a key role in migraine pathophysiology. The …