Heterozygous loss-of-function variants of the glucokinase (GCK) gene are responsible for a
subtype of maturity-onset diabetes of the young (MODY). GCK-MODY is characterized by a …

Glucokinase–maturity-onset diabetes of the young (GCK-MODY) is an autosomal dominant
disorder caused by heterozygous inactivating GCK gene mutations. GCK-MODY is one the …

Aims To determine the fetal and maternal outcomes in pregnant women with Glucokinase‐
Maturity onset diabetes of the young (GCK‐MODY). Methods We studied the obstetric and …

OBJECTIVE Identifying glucokinase monogenic diabetes (GCK-MODY) in pregnancy is
important, as management is different from management for other forms of gestational …

Heterozygous inactivating mutations of the glucokinase (GCK) gene are causing GCK-
MODY, one of the most common forms of the Maturity Onset Diabetes of the Young (MODY) …

Gestational diabetes mellitus (GDM) frequently provides the first presentation of glucose
intolerance in women with mutations in the glucokinase gene (GCK). Identifying such …

Aims To investigate the prevalence and clinical characteristics of heterozygotes of the
glucokinase gene mutations G264S and IVS8+ 2 in the extended pedigree of two patients …

Background Maturity‐onset diabetes of the young (MODY) caused by heterozygous
mutations in the glucokinase (GCK) gene typically presents with lifelong, stable, mild fasting …

Aims/hypothesis In pregnancies where the mother has glucokinase-MODY (GCK-MODY),
fetal growth is determined by fetal genotype. When the fetus inherits a maternal pathogenic …

Glucokinase is a key regulatory enzyme in the pancreatic beta‐cell. It plays a crucial role in
the regulation of insulin secretion and has been termed the glucose sensor in pancreatic …