Radiation-induced changes in skin and soft tissue result in significant cosmetic and
functional impairment with subsequent decrease in quality of life. Fat grafting has emerged …

Background: Autogenous fat grafting has been observed to alleviate the sequelae of chronic
radiodermatitis. To date, no study has replicated this finding in an animal model. Methods …

Background: Following radiation therapy, skin becomes fibrotic and can present a difficult
problem for reconstructive surgeons. There is an increasing belief that fat grafting under …

Radiotherapy (RT) helps cure and palliate thousands of patients with a range of malignant
diseases. A major drawback, however, is the collateral damage done to tissues surrounding …

Radiotherapy (RT) has become an indispensable part of oncologic treatment protocols for a
range of malignancies. However, a serious adverse effect of RT is radiodermatitis; almost …

The use of fat grafting as a treatment for radiation and thermal injury is a recent application
of a historically well-described operation. The autologous transplantation of fat has been …

Free autologous fat transfer was first described in 1893 when Franz Neuber reported the
harvest of fat from a patient's arm to fill a defect in the cheek cause by tuberculosis of the …

Fat injections aid in the healing of radiation-induced skin damage. We hypothesized that the
direct application of fat grafts to the surfaces of radiation-induced ulcers is also effective …

BACKGROUND: Fat grafting has been shown clinically to improve the quality of burn scars.
To date, no study has explored the mechanism of this effect. We aimed to do so by …

Objective: Problematic wound healing and ulceration in radiation-damaged tissue is a
surgical challenge. Clinical studies have shown that grafting fat tissue in an irradiated area …