Ankylosing spondylitis: etiology, pathogenesis, and treatments

W Zhu, X He, K Cheng, L Zhang, D Chen, X Wang… - Bone research, 2019 - nature.com
Ankylosing spondylitis (AS), a common type of spondyloarthropathy, is a chronic
inflammatory autoimmune disease that mainly affects spine joints, causing severe, chronic …

Ankylosing spondylitis risk factors: a systematic literature review

MC Hwang, L Ridley, JD Reveille - Clinical rheumatology, 2021 - Springer
Radiographic axial spondyloarthritis (also known as ankylosing spondylitis [AS]) is a chronic
immune-mediated arthritis characterized by inflammation of the axial skeleton, peripheral …

[HTML][HTML] Role of innate immune system in the pathogenesis of ankylosing spondylitis

N Vanaki, S Aslani, A Jamshidi, M Mahmoudi - Biomedicine & …, 2018 - Elsevier
Ankylosing Spondylitis (AS) is a debilitating rheumatic disease that gives young adults a
severe form of arthritis with pain and stiffness in the axial skeleton. After the discovery of …

Update on ankylosing spondylitis: current concepts in pathogenesis

JA Smith - Current allergy and asthma reports, 2015 - Springer
Ankylosing spondylitis is an insidiously progressive and debilitating form of arthritis involving
the axial skeleton. The long delay in diagnosis and insufficient response to currently …

Pathogenesis of ankylosing spondylitis—recent advances and future directions

V Ranganathan, E Gracey, MA Brown… - Nature Reviews …, 2017 - nature.com
Over the past 5 years, advances in high-throughput techniques and studies involving large
cohorts of patients have led to considerable advances in the identification of novel genetic …

[HTML][HTML] Recent advances in ankylosing spondylitis: understanding the disease and management

L Garcia-Montoya, H Gul, P Emery - F1000Research, 2018 - ncbi.nlm.nih.gov
The term spondyloarthritis refers to a group of immune-mediated diseases characterised by
inflammation of the axial skeleton, peripheral joints, and entheses. Ankylosing spondylitis …

New developments in our understanding of ankylosing spondylitis pathogenesis

A Voruganti, P Bowness - Immunology, 2020 - Wiley Online Library
Ankylosing spondylitis (AS) is a common immune‐mediated inflammatory arthritis with a
strong genetic predisposition. We review recent data from genetic and animal studies …

[HTML][HTML] Role of HLA-B27 in the pathogenesis of ankylosing spondylitis

B Chen, J Li, C He, D Li, W Tong… - Molecular medicine …, 2017 - spandidos-publications.com
The study of ankylosing spondylitis (AS) has made significant progress over the last decade.
Genome-wide association studies have identified and further substantiated the role of …

[HTML][HTML] Immune cells involved in the pathogenesis of ankylosing spondylitis

A Rezaiemanesh, M Abdolmaleki… - Biomedicine & …, 2018 - Elsevier
Ankylosing spondylitis (AS) is an inflammatory autoimmune disease. AS is a prototype form
of spondyloarthropathies (SpA). The precise etiology of AS has not been fully understood …

Pathogenesis of ankylosing spondylitis

LS Tam, J Gu, D Yu - Nature Reviews Rheumatology, 2010 - nature.com
Ankylosing spondylitis (AS) is a potentially disabling form of seronegative spondyloarthritis.
The main symptom of AS is inflammatory spinal pain; with time, some patients develop …