Background The dopamine D 2 receptor (D 2 R) has received much attention in obesity
studies. Data indicate that D 2 R is reduced in obesity and that the TaqA1 D 2 R variant may …

Anorexia nervosa (AN) is an eating disorder observed predominantly in women and girls
that is characterized by a low body-mass index, hypophagia, and hyperactivity. Activity …

The present study examined brain dopamine D2 and D4 receptor and tyrosine hydroxylase
(TH) mRNA expression in chronic high-fat diet-induced obese (cDIO) and obese-resistant …

Reports an error in" Dopamine D2 receptors in addiction-like reward dysfunction and
compulsive eating in obese rats" by Paul M. Johnson and Paul J. Kenny (Nature …

Dopaminergic signaling in the striatum, particularly at dopamine 2 receptors (D2R), has
been a topic of active investigation in obesity research in the past decades. However, it still …

In 2010, Johnson and Kenny provided conclusive evidence that extended access to a
Western-style diet promotes addictive-like behavior in rats by downregulating D2 receptors …

Dopamine (DA) signaling has been implicated in the control of energy balance and
ingestive behavior. In the present study, we sought to characterize body weight, body fat and …

Obesity is associated with physical inactivity, which exacerbates the health consequences of
weight gain. However, the mechanisms that mediate this association are unknown. We …

While there is a considerable body of literature correlating the role of dopaminergic genes
and obesity, body mass index, body type, overeating, carbohydrate binging, energy …

We found that development of obesity was coupled with emergence of a progressively
worsening deficit in neural reward responses. Similar changes in reward homeostasis …