Islet transplantation may be the most efficient therapeutic technique for patients with type 1
diabetes mellitus (T1DM). However, the clinical application of this method is faced with …

Islet transplantation is characterized by the transplantation of isolated islets from donor
pancreata into a diabetic recipient. Although it is a viable choice in the treatment of insulin …

Islet cell transplantation has therapeutic potential to treat type 1 diabetes, which is
characterized by autoimmune destruction of insulin-producing pancreatic islet β cells. It …

Islet transplantation is poised to play an important role in the treatment of type 1 diabetes
mellitus (T1DM). However, there are several challenges limiting its widespread use …

Islet transplantation has the potential to cure type 1 diabetes, but current clinical
transplantation protocols are inefficient because of the extensive loss of functional islets …

Islet transplantation is an established clinical procedure for select patients with type 1
diabetes and severe hypoglycemia to stabilize glycemic control. Post-transplant, substantial …

Type 1 diabetes is an autoimmune disorder that leads to destruction of pancreaticβ islet cells
and is a growing global health issue. While insulin replacement remains the standard …

Allogeneic islet transplantation serves as a source of insulin-secreting beta-cells for the
maintenance of normal glucose levels and treatment of diabetes. However, limited …

Pancreatic islet transplantation is an attractive option for treatment of type 1 diabetes mellitus
but maintaining long term islet function remains challenging. Mesenchymal stromal cells …

Background Islet transplantation is a commonly therapeutic strategy for diabetes mellitus.
However, avascular phase and the poor formation of blood vessels in the late period lead to …