Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema

WA Mould, JR Carhuapoma, J Muschelli, K Lane… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Perihematomal edema (PHE) can worsen outcomes after
intracerebral hemorrhage (ICH). Reports suggest that blood degradation products lead to …

Surgical performance determines functional outcome benefit in the minimally invasive surgery plus recombinant tissue plasminogen activator for intracerebral …

IA Awad, SP Polster, J Carrión-Penagos… - …, 2019 - journals.lww.com
BACKGROUND Minimally invasive surgery procedures, including stereotactic catheter
aspiration and clearance of intracerebral hemorrhage (ICH) with recombinant tissue …

Preliminary findings of the minimally-invasive surgery plus rtPA for intracerebral hemorrhage evacuation (MISTIE) clinical trial

T Morgan, M Zuccarello, R Narayan, P Keyl, K Lane… - Cerebral …, 2008 - Springer
Introduction Compared to ischemic stroke, intracerebral hemorrhage (ICH) is easily and
rapidly identified, occurs in younger patients, and produces relatively small initial injury to …

Long-term functional outcome following minimally invasive endoscopic intracerebral hemorrhage evacuation

CP Kellner, R Song, J Pan, DA Nistal… - Journal of …, 2020 - jnis.bmj.com
Background and purpose Preclinical studies suggest that clot removal may mitigate primary
and secondary brain injury following intracerebral hemorrhage (ICH). Although the MISTIE …

Ultra-early clot aspiration after lysis with tissue plasminogen activator in a porcine model of intracerebral hemorrhage: edema reduction and blood-brain barrier …

KR Wagner, G Xi, Y Hua, M Zuccarello… - Journal of …, 1999 - thejns.org
Object. Ultra-early hematoma evacuation (< 4 hours) after intracerebral hemorrhage (ICH)
may reduce mass effect and edema development and improve outcome. To test this …

Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded …

DF Hanley, RE Thompson, M Rosenblum, G Yenokyan… - The Lancet, 2019 - thelancet.com
Background Acute stroke due to supratentorial intracerebral haemorrhage is associated with
high morbidity and mortality. Open craniotomy haematoma evacuation has not been found …

Rate of perihaematomal oedema expansion is associated with poor clinical outcomes in intracerebral haemorrhage

SB Murthy, S Urday, LA Beslow, J Dawson… - Journal of Neurology …, 2016 - jnnp.bmj.com
Background Perihaematomal edema (PHE) expansion rate may be a predictor of outcome
after intracerebral haemorrhage (ICH). We determined whether PHE expansion rate in the …

Perihematomal edema and functional outcomes in intracerebral hemorrhage: influence of hematoma volume and location

SB Murthy, Y Moradiya, J Dawson, KR Lees… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Perihematomal edema (PHE) is associated with poor outcomes
after intracerebral hemorrhage (ICH). PHE evolves in the early period after ICH, providing a …

Safety and efficacy of minimally invasive surgery plus alteplase in intracerebral haemorrhage evacuation (MISTIE): a randomised, controlled, open-label, phase 2 trial

DF Hanley, RE Thompson, J Muschelli… - The Lancet …, 2016 - thelancet.com
Background Craniotomy, according to the results from trials, does not improve functional
outcome after intracerebral haemorrhage. Whether minimally invasive catheter evacuation …

Stereotactic aspiration-thrombolysis of intracerebral hemorrhage and its impact on perihematoma brain edema

JR Carhuapoma, RJ Barrett, PM Keyl, DF Hanley… - Neurocritical care, 2008 - Springer
Background Recent reports suggest that when thrombolytic agents are administered within
the clot, lysis rate accelerates at the expense of increased risk of worsening edema. To test …