The Potential Role of Viral Persistence in the Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

L Lupi, A Vitiello, C Parolin, A Calistri, A Garzino-Demo - Pathogens, 2024 - mdpi.com
The infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
associated not only with the development of acute disease but also with long-term symptoms …

Understanding the outcomes of COVID-19–does the current model of an acute respiratory infection really fit?

P Simmonds, S Williams… - Journal of General …, 2021 - microbiologyresearch.org
Although coronavirus disease 2019 (COVID-19) is regarded as an acute, resolving infection
followed by the development of protective immunity, recent systematic literature review …

Viral persistence, reactivation, and mechanisms of long COVID

B Chen, B Julg, S Mohandas, SB Bradfute - Elife, 2023 - elifesciences.org
The COVID-19 global pandemic caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection has infected hundreds of millions of individuals …

[HTML][HTML] Insights into the virologic and immunologic features of SARS-COV-2

C Polat, K Ergunay - World journal of clinical cases, 2021 - ncbi.nlm.nih.gov
The host immunity is crucial in determining the clinical course and prognosis of coronavirus
disease 2019, where some systemic and severe manifestations are associated with …

Persistence of SARS-CoV-2 RNA shedding and infectivity in immunized population: Prospective study along different epidemiological periods in Argentina

C Theaux, Y Martin, L Montoto Piazza, G Wenk… - PLoS …, 2023 - journals.plos.org
During the pandemic of COVID-19, numerous waves of infections affected the two
hemispheres with different impacts on each country. Throughout these waves, and with the …

Intrinsic factors behind long COVID: III. Persistence of SARS‐CoV‐2 and its components

NA El‐Baky, AA Amara, VN Uversky… - Journal of Cellular …, 2024 - Wiley Online Library
Considerable research has been done in investigating SARS‐CoV‐2 infection, its
characteristics, and host immune response. However, debate is still ongoing over the …

Inflammation, immunity, and antigen persistence in post-acute sequelae of SARS-CoV-2 infection

KL Newell, AT Waickman - Current Opinion in Immunology, 2022 - Elsevier
Highlights•Post-acute sequelae of SARS-CoV-2 (PASC) are associated with persistent
inflammation.•The antigens or other immune stimuli driving PASC are still unclear.•PASC …

A compromised specific humoral immune response against the SARS-CoV-2 receptor-binding domain is related to viral persistence and periodic shedding in the …

F Hu, F Chen, Z Ou, Q Fan, X Tan, Y Wang… - Cellular & molecular …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been redetected after
discharge in some coronavirus disease 2019 (COVID-19) patients. The reason for the …

Transmission of SARS-CoV-2: an update of current literature

KP Patel, SR Vunnam, PA Patel, KL Krill… - European Journal of …, 2020 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent for the
2019 coronavirus disease (COVID-19) pandemic, has caused a public health emergency …

Coronavirus persistence in human respiratory tract and cell culture: An overview

A Gaspar-Rodríguez, A Padilla-González… - Brazilian Journal of …, 2021 - SciELO Brasil
Emerging human coronaviruses, including the recently identified SARS-CoV-2, are relevant
respiratory pathogens due to their potential to cause epidemics with high case fatality rates …