Sarcopenic obesity is becoming a global health concern, owing to the rising older
population, causing cardiometabolic morbidity and mortality. Loss of muscle exceeding …

Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …

Age‐associated obesity and muscle atrophy (sarcopenia) are intimately connected and are
reciprocally regulated by adipose tissue and skeletal muscle dysfunction. During ageing …

Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

As a result of aging, body composition changes, with a decline in muscle mass and an
increase in adipose tissue (AT), which reallocates from subcutaneous to visceral depots and …

Highlights•Animal and cell culture work demonstrate that irisin, leptin, and adiponectin have
the potential to positively regulate skeletal muscle size.•Discrepancies between studies …

Skeletal muscle maintenance is a dynamic process and undergoes constant repair and
regeneration. However, skeletal muscle regenerative capacity declines in obesity. In this …

Skeletal muscle is a dynamic organ that responds to various stimuli by altering its size,
strength, and composition. Maintenance of skeletal muscle mass and strength is critical for …

The prevalence of sarcopenic obesity is increasing worldwide, particularly amongst aging
populations. Insulin resistance is the core mechanism of sarcopenic obesity and is also …

Sarcopenia is of important clinical relevance for loss of independence in older adults. The
prevalence of obesity in combination with sarcopenia ('sarcopenic-obesity') is increasing at …