Osteoarthritis (OA) is a degenerative disease that affects the synovial joints, especially the
knee joint, diminishing the ability of patients to perform daily physical activities …

Computational models can be used to predict the onset and progression of knee
osteoarthritis. Ensuring the transferability of these approaches among computational …

New technologies are required to support a radical shift towards preventive healthcare. Here
we focus on evaluating the possibility of finite element (FE) analysis-aided prevention of …

Our objective was to identify precise mechanical metrics of the proximal tibia which
differentiated OA and normal knees. We developed subject-specific FE models for 14 …

Little is known about knee‐specific factors that influence contact mechanics. Finite Element
(FE) models offer a powerful tool to study contact mechanics, but there often exists ambiguity …

Simulation studies, such as finite element (FE) modeling, provide insight into knee joint
mechanics without patient involvement. Generic FE models mimic the biomechanical …

Understanding how structural and functional alterations of individual tissues impact on
whole-joint function is challenging, particularly in humans where direct invasive …

The knee joint is a complex mechanical system, and computational modelling can provide
vital information for the prediction of disease progression and of the potential for therapeutic …

Knee osteoarthritis (OA) is a painful joint disease, causing disabilities in daily activities.
However, there is no known cure for OA, and the best treatment strategy might be …

Virtual representations of the knee joint can provide clinicians, scientists, and engineers the
tools to explore mechanical functions of the knee and its tissue structures in health and …