Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view

S Thietart, PE Rautou - Journal of hepatology, 2020 - Elsevier
Extracellular vesicles are membrane-bound vesicles containing proteins, lipids, RNAs and
microRNAs. They can originate from both healthy and stressed cells, and provide a …

Extracellular vesicles in liver diseases

S Maji, A Matsuda, IK Yan… - American Journal of …, 2017 - journals.physiology.org
Extracellular vesicles (EVs) are membrane-bound vesicles that are released by cells into
their extracellular environment, have selective enrichment of specific proteins and RNA, and …

Exosomes in liver pathology

K Sato, F Meng, S Glaser, G Alpini - Journal of hepatology, 2016 - Elsevier
Exosomes are small (∼ 100 nm) membrane-bound extracellular vesicles released by
various types of cells into biological fluids. They contain proteins, mRNAs and miRNAs as …

Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets

G Szabo, F Momen-Heravi - Nature reviews Gastroenterology & …, 2017 - nature.com
Extracellular vesicles (EVs) are membranous vesicles originating from different cells in the
liver. The pathophysiological role of EVs is increasingly recognized in liver diseases …

[HTML][HTML] Extracellular vesicles: a new frontier in biomarker discovery for non-alcoholic fatty liver disease

LA Ban, NA Shackel, SV McLennan - International journal of molecular …, 2016 - mdpi.com
In recent years, the global burden of obesity and diabetes has seen a parallel rise in other
metabolic complications, such as non-alcoholic fatty liver disease (NAFLD). This condition …

[HTML][HTML] Circulating cell-specific extracellular vesicles as biomarkers for the diagnosis and monitoring of chronic liver diseases

LA Newman, K Muller, A Rowland - Cellular and Molecular Life Sciences, 2022 - Springer
Chronic liver diseases represent a burgeoning health problem affecting billions of people
worldwide. The insufficient performance of current minimally invasive tools is recognised as …

Extracellular vesicles: Novel mediator for cell to cell communications in liver pathogenesis

PB Devhare, RB Ray - Molecular aspects of medicine, 2018 - Elsevier
Extracellular vesicles (EVs) are membrane derived nanometer-sized vesicles. EVs are
released by normal, diseased, and transformed cells in vitro and in vivo, and carry lipids …

Role of extracellular vesicles in liver diseases and their therapeutic potential

E Kostallari, S Valainathan, L Biquard, VH Shah… - Advanced drug delivery …, 2021 - Elsevier
More than eight hundred million people worldwide have chronic liver disease, with two
million deaths per year. Recurring liver injury results in fibrogenesis, progressing towards …

Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity

E Rodríguez-Suárez, E Gonzalez, C Hughes… - Journal of …, 2014 - Elsevier
Extracellular vesicles have created great interest as possible source of biomarkers for
different biological processes and diseases. Although the biological function of these …

Extracellular vesicles in liver pathobiology: small particles with big impact

P Hirsova, SH Ibrahim, VK Verma, LA Morton… - Hepatology, 2016 - journals.lww.com
Extracellular vesicles (EVs) are nanometer‐sized, membrane‐bound vesicles released by
cells into the extracellular milieu. EVs are now recognized to play a critical role in cell‐to‐cell …