[HTML][HTML] Pulmonary fibrosis: patterns and perpetrators

PW Noble, CE Barkauskas… - The Journal of clinical …, 2012 - Am Soc Clin Investig
Pulmonary fibrosis occurs in a variety of clinical settings, constitutes a major cause of
morbidity and mortality, and represents an enormous unmet medical need. However, the …

Immune mechanisms in pulmonary fibrosis

S Kolahian, IE Fernandez, O Eickelberg… - American journal of …, 2016 - atsjournals.org
Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis, represents a chronic and
progressive disease with high mortality and limited therapeutic options. Excessive …

Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies

B Selvarajah, M Platé, RC Chambers - Molecular Aspects of Medicine, 2023 - Elsevier
Fibrosis is the concluding pathological outcome and major cause of morbidity and mortality
in a number of common chronic inflammatory, immune-mediated and metabolic diseases …

Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group

RG Crystal, PB Bitterman, B Mossman… - American journal of …, 2002 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is an insidious inflammatory fibroproliferative disease
whose cause and course before diagnosis are unknown, and for which existing treatments …

Idiopathic pulmonary fibrosis: new insights in its pathogenesis

A Pardo, M Selman - The international journal of biochemistry & cell biology, 2002 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a unique type of chronic fibrosing lung disease of
unknown etiology. The sequence of the pathogenic mechanisms is unknown, but the …

Integrating mechanisms of pulmonary fibrosis

TA Wynn - Journal of Experimental Medicine, 2011 - rupress.org
Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …

Molecular mechanisms of and possible treatment strategies for idiopathic pulmonary fibrosis

M Gharaee-Kermani, SH Phan - Current pharmaceutical design, 2005 - ingentaconnect.com
Pulmonary fibrosis is characterized by lung inflammation and abnormal tissue repair,
resulting in the replacement of normal functional tissue with an abnormal accumulation of …

Idiopathic pulmonary fibrosis: from epithelial injury to biomarkers-insights from the bench side

M Kolb, K Borensztajn, B Crestani, M Kolb - Respiration, 2014 - karger.com
Idiopathic pulmonary fibrosis (IPF) is the most frequent fibrotic diffuse parenchymal lung
disease. Its prognosis is devastating:> 50% of the patients die within 3 years after diagnosis …

Progress in understanding and treating idiopathic pulmonary fibrosis

JA Kropski, TS Blackwell - Annual review of medicine, 2019 - annualreviews.org
This is a time of substantial progress in the evaluation and care of patients with idiopathic
pulmonary fibrosis (IPF). In addition to the approval and widespread availability of the first …

Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis

C Agostini, C Gurrieri - Proceedings of the American Thoracic …, 2006 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible fibrosing lung disease of
unknown etiology and with an unfavorable outcome, leading ultimately to death due to …