[HTML][HTML] Biofilms: Understanding the structure and contribution towards bacterial resistance in antibiotics

P Shree, CK Singh, KK Sodhi, JN Surya… - Medicine in …, 2023 - Elsevier
The biofilm is a bacterial colony wrapped in an auto-produced polymer matrix of
polysaccharides, proteins, and DNA. Bacterial biofilms cause persistent infections because …

Biofilms as promoters of bacterial antibiotic resistance and tolerance

C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Biofilms: microbial shelters against antibiotics

S Hathroubi, MA Mekni, P Domenico… - Microbial Drug …, 2017 - liebertpub.com
Biofilms are communities of aggregated bacterial cells embedded in a self-produced
extracellular polymeric matrix. Biofilms are recalcitrant to antibiotic treatment and immune …

Antibiotic resistance in biofilm

S Dincer, FM Uslu, A Delik - Bacterial biofilms, 2020 - books.google.com
Biofilms can be found on several living and nonliving surfaces, which are formed by a group
of microorganisms, complex assembly of proteins, polysaccharides, and DNAs in an …

Antibiotic resistance of bacterial biofilms

N Høiby, T Bjarnsholt, M Givskov, S Molin… - International journal of …, 2010 - Elsevier
A biofilm is a structured consortium of bacteria embedded in a self-produced polymer matrix
consisting of polysaccharide, protein and DNA. Bacterial biofilms cause chronic infections …

Tolerance and resistance of microbial biofilms

O Ciofu, C Moser, PØ Jensen, N Høiby - Nature Reviews Microbiology, 2022 - nature.com
Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …

Secondary effects of antibiotics on microbial biofilms

A Penesyan, IT Paulsen, MR Gillings… - Frontiers in …, 2020 - frontiersin.org
Biofilms are assemblages of microorganisms attached to each other, or to a surface, and
encased in a protective, self-produced matrix. Such associations are now recognized as the …

Innate and induced resistance mechanisms of bacterial biofilms

GG Anderson, GA O'toole - Bacterial biofilms, 2008 - Springer
Bacterial biofilms are highly recalcitrant to antibiotic treatment, which holds serious
consequences for therapy of infections that involve biofilms. The genetic mechanisms of this …

Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria

CW Hall, TF Mah - FEMS microbiology reviews, 2017 - academic.oup.com
Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …

Mechanisms of antibiotic resistance in bacterial biofilms

PS Stewart - International journal of medical microbiology, 2002 - Elsevier
Bacteria that attach to a surface and grow as a biofilm are protected from killing by
antibiotics. Reduced antibiotic susceptibility contributes to the persistence of biofilm …