Basophils bind IgE via FcεRI-αβγ2, which they uniquely share only with mast cells. In doing
so, they can rapidly release mediators that are hallmark of allergic disease. This …

Basophils are one of the rarest immune cell types, representing less than 1% of circulating
leucocytes in humans. They were discovered more than 140 years ago by Paul Ehrlich, but …

Basophils are the rarest blood cell population and have not been extensively studied. Our
understanding of the functions of basophils is limited to their roles as the main effector cells …

Until recently, basophils had often been neglected in immunologic studies because of their
minority status among immune cells or confused with tissue-resident mast cells because of …

Basophils, the rarest granulocytes, were identified by Paul Ehrlich more than 140 years ago,
much earlier than the discovery of T and B cells. Unfortunately, basophils were often mixed …

Basophils are the rarest granulocytes which represent< 1% of peripheral blood leukocytes.
Basophils bear several phenotypic similarities to tissue‐resident mast cells and therefore …

Basophils were discovered by Paul Ehrlich in 1879 and represent the least abundant
granulocyte population in mammals. The relative rarity of basophils and their phenotypic …

Basophils have emerged in recent years as a small but potent subpopulation of leukocytes
capable of bridging innate and adaptive immunity. They can be activated through IgE …

Basophils are functionally closely related to mast cells. Both cell types express the high-
affinity IgE receptor (FcεRI) and rapidly release preformed mediator from intracellular stores …

Basophils are mainly known as pro-inflammatory effector cells associated with allergy and
helminth infections. Although they were identified over 130 years ago, their in vivo functions …