Genome‐wide analysis of DNA methylation in relation to socioeconomic status during development and early adulthood
Objectives Socioeconomic status (SES) is a powerful determinant of health, but the
underlying biological mechanisms are poorly understood. This study investigates whether …
underlying biological mechanisms are poorly understood. This study investigates whether …
The biological embedding of early-life socioeconomic status and family adversity in children's genome-wide DNA methylation
Aim: To examine variation in child DNA methylation to assess its potential as a pathway for
effects of childhood social adversity on health across the life course. Materials & methods: In …
effects of childhood social adversity on health across the life course. Materials & methods: In …
Individual variation and longitudinal pattern of genome-wide DNA methylation from birth to the first two years of life
Prenatal development and early childhood are critical periods for establishing the tissue-
specific epigenome, and may have a profound impact on health and disease in later life …
specific epigenome, and may have a profound impact on health and disease in later life …
DNA methylation at stress‐related genes is associated with exposure to early life institutionalization
Objectives Differences in DNA methylation have been associated with early life adversity,
suggesting that alterations in methylation function as one pathway through which adverse …
suggesting that alterations in methylation function as one pathway through which adverse …
Associations with early-life socio-economic position in adult DNA methylation
N Borghol, M Suderman, W McArdle… - International journal …, 2012 - academic.oup.com
Background Disadvantaged socio-economic position (SEP) in childhood is associated with
increased adult mortality and morbidity. We aimed to establish whether childhood SEP was …
increased adult mortality and morbidity. We aimed to establish whether childhood SEP was …
Factors underlying variable DNA methylation in a human community cohort
Epigenetics is emerging as an attractive mechanism to explain the persistent genomic
embedding of early-life experiences. Tightly linked to chromatin, which packages DNA into …
embedding of early-life experiences. Tightly linked to chromatin, which packages DNA into …
DNA methylation-based variation between human populations
F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
Several studies have proved that DNA methylation affects regulation of gene expression and
development. Epigenome-wide studies have reported variation in methylation patterns …
development. Epigenome-wide studies have reported variation in methylation patterns …
Ancestry dependent DNA methylation and influence of maternal nutrition
There is extensive variation in DNA methylation between individuals and ethnic groups.
These differences arise from a combination of genetic and non-genetic influences and …
These differences arise from a combination of genetic and non-genetic influences and …
DNA methylation contributes to natural human variation
DNA methylation patterns are important for establishing cell, tissue, and organism
phenotypes, but little is known about their contribution to natural human variation. To …
phenotypes, but little is known about their contribution to natural human variation. To …
Associations between indicators of socioeconomic position and DNA methylation: a scoping review
Background Socioeconomic position (SEP) is a major determinant of health across the life
course. Yet, little is known about the biological mechanisms explaining this relationship. One …
course. Yet, little is known about the biological mechanisms explaining this relationship. One …
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