[HTML][HTML] The role of hydrogen peroxide in redox-dependent signaling: homeostatic and pathological responses in mammalian cells

N Di Marzo, E Chisci, R Giovannoni - Cells, 2018 - mdpi.com
Hydrogen peroxide (H2O2) is an important metabolite involved in most of the redox
metabolism reactions and processes of the cells. H2O2 is recognized as one of the main …

[HTML][HTML] Chemistry of hydrogen peroxide formation and elimination in mammalian cells, and its role in various pathologies

CMC Andrés, JM Pérez de la Lastra, CA Juan, FJ Plou… - Stresses, 2022 - mdpi.com
Hydrogen peroxide (H2O2) is a compound involved in some mammalian reactions and
processes. It modulates and signals the redox metabolism of cells by acting as a messenger …

Hydrogen peroxide: a signaling messenger

JR Stone, S Yang - Antioxidants & redox signaling, 2006 - liebertpub.com
Hydrogen peroxide (H2O2) is a well-documented component of living cells. It plays
important roles in host defense and oxidative biosynthetic reactions. In addition there is …

Methods to detect hydrogen peroxide in living cells: Possibilities and pitfalls

MB Grisham - Comparative Biochemistry and Physiology Part A …, 2013 - Elsevier
Intracellular generation of reactive oxygen species (ROS) is an inescapable consequence of
aerobic metabolism. Although some of these oxygen-derived metabolites are well …

[HTML][HTML] Hydrogen peroxide–production, fate and role in redox signaling of tumor cells

C Lennicke, J Rahn, R Lichtenfels… - Cell communication and …, 2015 - Springer
Abstract Hydrogen peroxide (H 2 O 2) is involved in various signal transduction pathways
and cell fate decisions. The mechanism of the so called “redox signaling” includes the H 2 O …

Hydrogen peroxide as a cell-survival signaling molecule

G Groeger, C Quiney, TG Cotter - Antioxidants & redox signaling, 2009 - liebertpub.com
Reactive oxygen species (ROS) were seen as destructive molecules, but recently, they have
been shown also to act as second messengers in varying intracellular signaling pathways …

[PDF][PDF] Hydrogen peroxide sensing and signaling

EA Veal, AM Day, BA Morgan - Molecular cell, 2007 - cell.com
It is well established that oxidative stress is an important cause of cell damage associated
with the initiation and progression of many diseases. Consequently, all air-living organisms …

Hydrogen peroxide as a signaling molecule

E Veal, A Day - Antioxidants & redox signaling, 2011 - liebertpub.com
Increases in hydrogen peroxide can initiate protective responses to limit or repair oxidative
damage. However, hydrogen peroxide signals also fine-tune responses to growth factors …

[HTML][HTML] Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

H Sies - Redox biology, 2017 - Elsevier
Hydrogen peroxide emerged as major redox metabolite operative in redox sensing,
signaling and redox regulation. Generation, transport and capture of H 2 O 2 in biological …

[HTML][HTML] Role of metabolic H2O2 generation: redox signaling and oxidative stress

H Sies - Journal of Biological Chemistry, 2014 - ASBMB
Hydrogen peroxide, the nonradical 2-electron reduction product of oxygen, is a normal
aerobic metabolite occurring at about 10 nm intracellular concentration. In liver, it is …