Nanocarriers: A novel strategy for the delivery of CRISPR/Cas systems

F Hejabi, MS Abbaszadeh, S Taji, A O'Neill… - Frontiers in …, 2022 - frontiersin.org
In recent decades, clustered regularly interspaced short palindromic repeat/CRISPR-
associated protein (CRISPR/Cas) has become one of the most promising genome-editing …

Non-viral nanocarriers for CRISPR-Cas9 gene editing system delivery

X Tang, Z Wang, Y Zhang, W Mu, X Han - Chemical Engineering Journal, 2022 - Elsevier
Clustered regularly interspaced short palindromic repeat-associated protein 9 (CRISPR-
Cas9) is a powerful gene editing tool for treating disease. The safe and effective delivery of …

Nanoparticle delivery of CRISPR/Cas9 for genome editing

L Duan, K Ouyang, X Xu, L Xu, C Wen, X Zhou… - Frontiers in …, 2021 - frontiersin.org
The emerging clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-
associated system (Cas) gene-editing system represents a promising tool for genome …

Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities

L Li, S Hu, X Chen - Biomaterials, 2018 - Elsevier
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas
(CRISPR-associated) genome editing systems have become one of the most robust …

Lipid-and polymer-based nanoparticle systems for the delivery of CRISPR/Cas9

B Ashok, NA Peppas, ME Wechsler - Journal of drug delivery science and …, 2021 - Elsevier
The discovery of clustered regularly interspaced short palindromic repeat
(CRISPR)/CRISPR-associated (Cas) genome editing systems and their applications in …

Synthetic vehicles for encapsulation and delivery of CRISPR/Cas9 gene editing machinery

V Carboni, C Maaliki, M Alyami, S Alsaiari… - Advanced …, 2019 - Wiley Online Library
Clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR‐
associated 9 (Cas‐9) technology holds tremendous potential as a gene editing tool …

Carrier strategies boost the application of CRISPR/Cas system in gene therapy

Z Xu, Q Wang, H Zhong, Y Jiang, X Shi, B Yuan… - …, 2022 - Wiley Online Library
Emerging clustered regularly interspaced short palindromic repeat/associated protein
(CRISPR/Cas) genome editing technology shows great potential in gene therapy. However …

Current and prospective strategies for advancing the targeted delivery of CRISPR/Cas system via extracellular vesicles

X Huang, A Li, P Xu, Y Yu, S Li, L Hu… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) have emerged as a promising platform for gene delivery owing
to their natural properties and phenomenal functions, being able to circumvent the …

Synthetic multi-layer nanoparticles for CRISPR-Cas9 genome editing

H Tang, X Zhao, X Jiang - Advanced drug delivery reviews, 2021 - Elsevier
The clustered regularly interspaced short palindromic repeat (CRISPR) has great potential
to revolutionize biomedical research and disease therapy. The specific and efficient genome …

Synthetic nanoparticles for the delivery of CRISPR/Cas9 gene editing system: classification and biomedical applications

Q Zheng, W Wang, Y Zhou, J Mo, X Chang, Z Zha… - Biomaterials …, 2023 - pubs.rsc.org
Gene editing has great potential in biomedical research including disease diagnosis and
treatment. Clustered regularly interspaced short palindromic repeats (CRISPR) is the most …