[HTML][HTML] Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products

K Yeshi, R Ruscher, L Hunter, NL Daly… - Journal of clinical …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …

Emerging pharmacotherapy for inflammatory bowel diseases

H Luo, G Cao, C Luo, D Tan, CT Vong, Y Xu… - Pharmacological …, 2022 - Elsevier
Inflammatory bowel disease (IBD) refers to a gamut of disorders that are characterized by
chronic intestinal inflammation, including ulcerative colitis (UC) and Crohn's disease (CD) …

From the updated landscape of the emerging biologics for IBDs treatment to the new delivery systems

J Yang, D Li, M Zhang, G Lin, S Hu, H Xu - Journal of Controlled Release, 2023 - Elsevier
Inflammatory bowel diseases (IBDs) treatments have shifted from small-molecular
therapeutics to the oncoming biologics. The first-line biologics against the moderate-to …

New biologics and small molecules in inflammatory bowel disease: an update

J Sabino, B Verstockt, S Vermeire… - Therapeutic …, 2019 - journals.sagepub.com
Inflammatory bowel disease (IBD) is a spectrum of immune-mediated inflammatory disorders
with a complex multifactorial pathogenesis, where different pathways may predominate in …

Phytochemicals and their potential usefulness in inflammatory bowel disease

SJ Somani, KP Modi, AS Majumdar… - Phytotherapy …, 2015 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract with unclear etiology, namely ulcerative colitis and Crohn's disease. Various drug …

New therapies for inflammatory bowel disease: from the bench to the bedside

S Danese - Gut, 2012 - gut.bmj.com
The mechanisms underlying the chronic intestinal inflammation that is a hallmark of
inflammatory bowel diseases (IBD) are complex. Components of the pathological response …

[HTML][HTML] Pathogenesis of inflammatory bowel disease and recent advances in biologic therapies

DH Kim, JH Cheon - Immune network, 2017 - synapse.koreamed.org
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disorder with an
unknown etiology. IBD is composed of two different disease entities: Crohn's disease (CD) …

[HTML][HTML] Treatment of inflammatory bowel disease: a comprehensive review

Z Cai, S Wang, J Li - Frontiers in medicine, 2021 - frontiersin.org
Inflammatory bowel disease (IBD), as a global disease, has attracted much research
interest. Constant research has led to a better understanding of the disease condition and …

Newer biologic and small-molecule therapies for inflammatory bowel disease

DC Baumgart, C Le Berre - New England Journal of Medicine, 2021 - Mass Medical Soc
Newer Biologic and Small-Molecule Therapies for IBD There is still no cure for inflammatory
bowel disease. This review covers newer treatments that reflect our understanding of the …

Future therapeutic approaches for inflammatory bowel diseases

SE Plevy, SR Targan - Gastroenterology, 2011 - Elsevier
In this review, we speculate about future therapeutic approaches for inflammatory bowel
diseases (IBDs), focusing on the need for better preclinical and clinical models and …