Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan
We describe the collection of cohorts together with the analysis plan for an update of the
fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource …
fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource …
Pitfalls in the external validation of FRAX
JA Kanis, A Oden, H Johansson… - Osteoporosis International, 2012 - Springer
Recent studies have evaluated the performance of FRAX® in independent cohorts. The
interpretation of most is problematic for reasons summarised in this perspective. Introduction …
interpretation of most is problematic for reasons summarised in this perspective. Introduction …
Interpretation and use of FRAX in clinical practice
The introduction of the WHO FRAX® algorithms has facilitated the assessment of fracture
risk on the basis of fracture probability. Its use in fracture risk prediction has strengths, but …
risk on the basis of fracture probability. Its use in fracture risk prediction has strengths, but …
A brief history of FRAX
This paper reviews the research programme that went into the development of FRAX® and
its impact in the 10 years since its release in 2008. Introduction Osteoporosis is defined on …
its impact in the 10 years since its release in 2008. Introduction Osteoporosis is defined on …
Independent clinical validation of a Canadian FRAX tool: fracture prediction and model calibration
A FRAX model for Canada was constructed for prediction of osteoporotic and hip fracture
risk using national hip fracture data with and without the use of femoral neck bone mineral …
risk using national hip fracture data with and without the use of femoral neck bone mineral …
Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos
LA Fraser, L Langsetmo, C Berger, G Ioannidis… - Osteoporosis …, 2011 - Springer
A new Canadian WHO fracture risk assessment (FRAX®) tool to predict 10-year fracture
probability was compared with observed 10-year fracture outcomes in a large Canadian …
probability was compared with observed 10-year fracture outcomes in a large Canadian …
A systematic review of intervention thresholds based on FRAX: a report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis …
This systematic review identified assessment guidelines for osteoporosis that incorporate
FRAX. The rationale for intervention thresholds is given in a minority of papers. Intervention …
FRAX. The rationale for intervention thresholds is given in a minority of papers. Intervention …
From relative risk to absolute fracture risk calculation: the FRAX algorithm
EV McCloskey, H Johansson, A Oden… - Current osteoporosis …, 2009 - Springer
FRAX is a computer-based algorithm that provides models for the assessment of fracture
probability in men and women (http://www. shef. ac. uk/FRAX). The approach uses easily …
probability in men and women (http://www. shef. ac. uk/FRAX). The approach uses easily …
FRAX® tool, the WHO algorithm to predict osteoporotic fractures: the first analysis of its discriminative and predictive ability in the Spanish FRIDEX cohort
Background The WHO has recently published the FRAX® tool to determine the absolute risk
of osteoporotic fracture at 10 years. This tool has not yet been validated in Spain …
of osteoporotic fracture at 10 years. This tool has not yet been validated in Spain …
Assessment of individual fracture risk: FRAX and beyond
JPW van den Bergh, TACM van Geel, WF Lems… - Current osteoporosis …, 2010 - Springer
Abstract The World Health Organization fracture risk assessment tool (FRAX) and the
Garvan fracture risk calculator are both widely available tools for individualized fracture risk …
Garvan fracture risk calculator are both widely available tools for individualized fracture risk …