Bone marrow mesenchymal stem cell-derived exosomes promote tendon regeneration by facilitating the proliferation and migration of endogenous tendon stem …

H Yu, J Cheng, W Shi, B Ren, F Zhao, Y Shi, P Yang… - Acta biomaterialia, 2020 - Elsevier
Mesenchymal stem cells (MSCs)-derived exosomes are being increasingly focused as the
new biological pro-regenerative therapeutic agents for various types of tissue injury. Here …

[HTML][HTML] Therapeutic potential and mechanisms of mesenchymal stem cell-derived exosomes as bioactive materials in tendon–bone healing

J Zou, W Yang, W Cui, C Li, C Ma, X Ji, J Hong… - Journal of …, 2023 - Springer
Tendon–bone insertion (TBI) injuries, such as anterior cruciate ligament injury and rotator
cuff injury, are the most common soft tissue injuries. In most situations, surgical …

[HTML][HTML] Tendon stem cell-derived exosomes regulate inflammation and promote the high-quality healing of injured tendon

M Zhang, H Liu, Q Cui, P Han, S Yang, M Shi… - Stem cell research & …, 2020 - Springer
Abstract Background Tendon stem cells (TSCs) have been reported to hold promises for
tendon repair and regeneration. However, less is known about the effects of exosomes …

[HTML][HTML] Exosomes from tendon derived stem cells promote tendon repair through miR-144-3p-regulated tenocyte proliferation and migration

K Song, T Jiang, P Pan, Y Yao, Q Jiang - Stem cell research & therapy, 2022 - Springer
Background Tendon derived stem cells (TDSCs) have proven to be effective in tendon repair
by secreting paracrine factors, which modulate the function of resident cells and …

Exosomes from tendon stem cells promote injury tendon healing through balancing synthesis and degradation of the tendon extracellular matrix

Y Wang, G He, Y Guo, H Tang, Y Shi… - Journal of Cellular …, 2019 - Wiley Online Library
Tendon injuries are common musculoskeletal system disorders in clinical, but the
regeneration ability of tendon is limited. Tendon stem cells (TSCs) have shown promising …

[HTML][HTML] Exosomes derived from bone marrow stromal cells (BMSCs) enhance tendon-bone healing by regulating macrophage polarization

Y Shi, X Kang, Y Wang, X Bian, G He… - … medical journal of …, 2020 - ncbi.nlm.nih.gov
Background Inflammation after tendon-bone junction injury results in the formation of
excessive scar tissue and poor biomechanical properties. Recent research has shown that …

[HTML][HTML] Bone marrow mesenchymal stem cell-derived exosomes promote rotator cuff tendon-bone healing by promoting angiogenesis and regulating M1 …

Y Huang, B He, L Wang, B Yuan, H Shu… - Stem Cell Research & …, 2020 - Springer
Abstract Background Rotator cuff tears (RCTs) often require reconstructive surgery. Tendon-
bone healing is critical for the outcome of rotator cuff reconstruction, but the process of …

[HTML][HTML] MicroRNA engineered umbilical cord stem cell-derived exosomes direct tendon regeneration by mTOR signaling

Z Yao, J Li, H Xiong, H Cui, J Ning, S Wang… - Journal of …, 2021 - Springer
Background Exosomes are extracellular vesicles of nano-structures and represent an
emerging nano-scale acellular therapy in recent years. Tendon regeneration is a …

[HTML][HTML] Exosomes derived from magnetically actuated bone mesenchymal stem cells promote tendon-bone healing through the miR-21-5p/SMAD7 pathway

XD Wu, L Kang, J Tian, Y Wu, Y Huang, J Liu… - Materials Today Bio, 2022 - Elsevier
Graft healing after anterior cruciate ligament reconstruction (ACLR) involves slow biological
processes, and various types of biological modulations have been explored to promote …

[HTML][HTML] BMSC-derived exosomes promote tendon-bone healing after anterior cruciate ligament reconstruction by regulating M1/M2 macrophage polarization in rats

Z Li, Q Li, K Tong, J Zhu, H Wang, B Chen… - Stem Cell Research & …, 2022 - Springer
Background Recent studies have shown that bone marrow stromal cell-derived exosomes
(BMSC-Exos) can be used for tissue repair. However, whether the BMSC-Exos can promote …