Some genetic abnormalities of multiple myeloma (MM) detected more than two decades ago
remain major prognostic factors. In recent years, the introduction of cutting-edge genomic …

The genetics of myeloma has been increasingly elucidated in recent years. Recurrent
genetic events, and also biologically distinct and clinically relevant genetic subtypes of …

Multiple myeloma (MM) is a plasma cell neoplasm that accounts for 2% of all haematological
malignancies and predominantly affects older individuals (with a median age at diagnosis of …

Multiple myeloma (MM), one of the most intractable malignancies, is characterized by the
infiltration and growth of plasma cells, the most differentiated cells in the B-cell lineage, in …

Multiple myeloma (MM) is a complex disease that is driven by numerous genetic and
epigenetic alterations. Comprehensive oncogenomic analysis indicates the presence of …

PURPOSE Multiple myeloma (MM) is accompanied by heterogeneous somatic alterations.
The overall goal of this study was to describe the genomic landscape of myeloma using …

Multiple myeloma (MM) is a genetically complex disease that evolves from pre-malignant
stages, such as monoclonal gammaopathy of undetermined significance and smouldering …

Our knowledge of myeloma genetics remained limited and lagged behind many other
hematologic malignancies because of the inherent difficulties in generating metaphases …

Over the past few years, the management of multiple myeloma has changed. We have new
guidelines regarding how to set the diagnosis, when to initiate therapy, and how to monitor …

Multiple myeloma (MM) is characterized by a significant heterogeneity at the molecular level.
The first level is the chromosomal one. Although cytogenetics is difficult to assess in MM …