Antimicrobial peptides provide wider coverage for targeting drug‐resistant bacterial pathogens

AS Amiss, ST Henriques, N Lawrence - Peptide Science, 2022 - Wiley Online Library
We need new treatment options to control bacterial infections. Bacteria use several
strategies to resist drug treatment, including modification of the drug target, and adaptation …

Antimicrobial peptides as novel therapeutic agents to combat drug-resistant microbial infections

N Sitaram, R Nagaraj - Current Medicinal Chemistry-Anti …, 2002 - ingentaconnect.com
The discovery of penicillin and the tremendous success achieved in preventing fatalities due
to microbial infections by using it as a therapeutic antibiotic was perhaps the starting point of …

Therapeutic peptides: new arsenal against drug resistant pathogens

W WK Mok, Y Li - Current pharmaceutical design, 2014 - ingentaconnect.com
Our incessant tug-of-war with multidrug resistant pathogenic bacteria has prompted
researchers to explore novel methods of designing therapeutics in order to defend ourselves …

Mechanisms of antimicrobial peptide action and resistance

MR Yeaman, NY Yount - Pharmacological reviews, 2003 - ASPET
Antimicrobial peptides have been isolated and characterized from tissues and organisms
representing virtually every kingdom and phylum, ranging from prokaryotes to humans. Yet …

Novel peptide therapeutics for treatment of infections

PCF Oyston, MA Fox, SJ Richards… - Journal of medical …, 2009 - microbiologyresearch.org
As antibiotic resistance increases worldwide, there is an increasing pressure to develop
novel classes of antimicrobial compounds to fight infectious disease. Peptide therapeutics …

Antimicrobial peptides

M Malmsten - Upsala journal of medical sciences, 2014 - Taylor & Francis
With increasing antibiotics resistance, there is an urgent need for novel infection
therapeutics. Since antimicrobial peptides provide opportunities for this, identification and …

[HTML][HTML] Antimicrobial Peptides Demonstrate Activity against Resistant Bacterial Pathogens

M Garvey - Infectious Disease Reports, 2023 - mdpi.com
The antimicrobial resistance crisis is an ongoing major threat to public health safety. Low-
and middle-income countries are particularly susceptible to higher fatality rates and the …

[HTML][HTML] Antimicrobial peptide mimics for clinical use: does size matter?

J Svenson, N Molchanova, CI Schroeder - Frontiers in Immunology, 2022 - frontiersin.org
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …

Antibacterial peptides-a bright future or a false hope

R Bucki, I Levental, PA Janmey - Anti-Infective Agents in …, 2007 - ingentaconnect.com
The increasing number of antibiotic resistant bacterial strains presents an emerging world
health problem that demands continued effort to develop new antibacterial compounds …

Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides

V Lázár, A Martins, R Spohn, L Daruka, G Grézal… - Nature …, 2018 - nature.com
Antimicrobial peptides are promising alternative antimicrobial agents. However, little is
known about whether resistance to small-molecule antibiotics leads to cross-resistance …