Modulation of mitochondrial bioenergetics and glycolysis in malignancies has recently
emerged a potential chemotherapeutic strategy since numerous malignant cells have …

Abstract Changes in mitochondrial ATP synthesis can affect the function of tumor cells due to
the dependence of the first step of glycolysis on mitochondrial ATP. The oxidative …

Recent evidence highlights that energy requirements of cancer cells vary greatly from
normal cells and they exhibit different metabolic phenotypes with variable participation of …

Dietary phytochemicals have been shown to be chemopreventive against various types of
cancer. This study was designed to investigate the enhancement of the chemoresponse to …

Simple Summary In the present study, we synthesized and characterized the
physicochemical properties and anticancer activity of three non-polar, mitochondria-targeted …

Background Recent research has revealed that targeting mitochondrial bioenergetic
metabolism is a promising chemotherapeutic strategy. Key to successful implementation of …

As a major dietary flavonol, quercetin mitigates proliferation and progression of cancer due
to its anti‐angiogenic, anti‐inflammatory, anti‐oxidant, and apoptotic biological effects on …

Quercetin is a flavonoid with promising therapeutic applications; nonetheless, the phenotype
exerted in some diseases is contradictory. For instance, anticancer properties may be …

With increasing use of natural plant-derived components, exploring the anti-proliferative
effects of phytochemicals is increasingly gaining importance in designing anticancer drugs …

Purpose Walnut phenolic extract (WPE) reduces proliferation and enhances differentiation of
colon cancer stem cells (CSCs). The present study investigated the metabolic influence of …