The cell origin and role of osteoclastogenesis and osteoblastogenesis in vascular calcification

W Jiang, Z Zhang, Y Li, C Chen, H Yang… - Frontiers in …, 2021 - frontiersin.org
Arterial calcification refers to the abnormal deposition of calcium salts in the arterial wall,
which results in vessel lumen stenosis and vascular remodeling. Studies increasingly show …

A novel role of cellular interactions in vascular calcification

ASA Bardeesi, J Gao, K Zhang, S Yu, M Wei… - Journal of translational …, 2017 - Springer
A series of clinical trials have confirmed the correlation between vascular calcification (VC)
and cardiovascular events and mortality. However, current treatments have little effects on …

Vascular calcification: New insights into endothelial cells

C Yuan, L Ni, C Zhang, X Hu, X Wu - Microvascular Research, 2021 - Elsevier
Vascular calcification, a common pathological basis of vascular disease, is caused by
various diseases and is an independent risk factor for cardiovascular events. Therefore …

Rationale for the role of osteoclast‐like cells in arterial calcification

TM Doherty, H Uzui, LA Fitzpatrick… - The FASEB …, 2002 - Wiley Online Library
Atherosclerotic arteries frequently become calcified, and these calcium deposits are
associated with a high risk of adverse clinical events. Descriptive studies suggest …

[HTML][HTML] Roles of vascular smooth muscle cells in atherosclerotic calcification

SH Woo, DY Kim, JH Choi - Journal of Lipid and Atherosclerosis, 2023 - ncbi.nlm.nih.gov
The accumulation of calcium in atherosclerotic plaques is a prominent feature of advanced
atherosclerosis, and it has a strong positive correlation with the total burden of …

Cell phenotype transitions in cardiovascular calcification

L Hortells, S Sur, C St. Hilaire - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Cardiovascular calcification was originally considered a passive, degenerative process,
however with the advance of cellular and molecular biology techniques it is now appreciated …

Vascular calcification and bone disease: the calcification paradox

V Persy, P D'Haese - Trends in molecular medicine, 2009 - cell.com
Vascular calcification or ectopic mineralization in blood vessels is an active, cell-regulated
process, increasingly recognized as a general cardiovascular risk factor. Remarkably …

Circulating cellular players in vascular calcification

M Albiero, A Avogaro… - Current Pharmaceutical …, 2014 - ingentaconnect.com
Vascular calcification is the deposition of calcium-phosphate salts in the form of
hydroxyapatite within the arterial wall. This is a finely regulated process to such an extent …

Regulatory circuits controlling vascular cell calcification

T Sallam, H Cheng, LL Demer, Y Tintut - Cellular and molecular life …, 2013 - Springer
Vascular calcification is a common feature of chronic kidney disease, cardiovascular
disease, and aging. Such abnormal calcium deposition occurs in medial and/or intimal …

Vascular calcification: mechanisms of vascular smooth muscle cell calcification

JA Leopold - Trends in cardiovascular medicine, 2015 - Elsevier
Vascular calcification is highly prevalent and, when present, is associated with major
adverse cardiovascular events. Vascular smooth muscle cells play an integral role in …