In this review, we analyze the effects of growth hormone on a number of tissues and organs
and its putative role in the longitudinal growth of an organism. We conclude that the …

In this review we consider the evidence that growth hormone (GH) acts in the embryo as a
local growth, differentiation, and cell survival factor. Because both GH and its receptors are …

Growth hormone (GH) plays an important regulatory role in determining the rate of postnatal
somatic growth in many species, and ultimately determines final statural size. Other …

Growth hormone (GH) is an ancestral hormone secreted episodically from somatotroph cells
in the anterior pituitary. Since the recognition of its multiple and complex effects in the early …

Growth assessment is an essential component of pediatric examination. Stature is a
sensitive and accurate index of a child's health; any chronic health problem “from organic to …

Growth hormone (GH) is important for promotion of somatic growth and the regulation of
substrate metabolism. Metabolic action of GH occurs in multiple tissues including the liver …

GH may exert metabolic effects either directly or indirectly through increased production of
IGF-I. GH administration increases circulating IGF-I levels via stimulation of hepatic synthesis …

Growth hormone (GH) research and its clinical application for the treatment of growth
disorders span more than a century. During the first half of the 20th century, clinical …

The insulin and growth hormone (GH)/insulin-like growth factor-I (IGF-I) axis are two
endocrine systems that are interlinked at many levels. GH is one of the glucose counter …

I. Introduction G ROWTH hormone and the insulin-like growth factors (IGFs) compile a
complex, interrelated system of three peptide hormones, GH, IGF-I, and IGF-II, their specific …