Controlled release of drug and better bioavailability using poly (lactic acid-co-glycolic acid) nanoparticles

SK Pandey, DK Patel, AK Maurya, R Thakur… - International journal of …, 2016 - Elsevier
Tamoxifen (Tmx) embedded poly (lactic-co-glycolic acid)(PLGA) nanoparticles (PLGA-Tmx)
is prepared to evaluate its better DNA cleavage potential, cytotoxicity using Dalton's …

Therapeutic efficacy and toxicity of tamoxifen loaded PLA nanoparticles for breast cancer

SK Pandey, S Ghosh, P Maiti, C Haldar - International journal of biological …, 2015 - Elsevier
This study was carried out to assess the therapeutic efficacy and toxicity of tamoxifen (Tmx)
loaded poly (d, l-lactic acid)(PLA) nanoparticles (Tmx-NPs) for breast cancer. An in vivo …

Preparation and characterization of PLGA–PEG–PLGA nanoparticles containing salidroside and tamoxifen for breast cancer therapy

X Yu, L Sun, L Tan, M Wang, X Ren, J Pi, M Jiang… - AAPS …, 2020 - Springer
Nanoparticles (NPs) containing the hydrophilic drug salidroside (Sal) and the hydrophobic
drug tamoxifen (Tam) were prepared using a triblock copolymer poly (lactic-co-glycolic …

Tamoxifen-loaded poly (L-lactide) nanoparticles: development, characterization and in vitro evaluation of cytotoxicity

C Altmeyer, TK Karam, NM Khalil… - Materials Science and …, 2016 - Elsevier
In this study, poly (L-lactide)(PLA) nanoparticles containing Tamoxifen (Tmx) were
developed using an emulsion/solvent evaporation method, observing the influence of …

Tamoxifen citrate-loaded poly(d,l) lactic acid nanoparticles: Evaluation for their anticancer activity in vitro and in vivo

NR Ravikumara, M Bharadwaj… - Journal of …, 2016 - journals.sagepub.com
The optimization of tamoxifen citrate entrapment and its release from biodegradable poly (d,
l) lactic acid nanoparticles are prepared by modified spontaneous emulsification solvent …

Poly (D, L-lactide-co-glycolide) nanoparticles encapsulated fluorescent isothiocyanate and paclitaxol: preparation, release kinetics and anticancer effect

H Yang, K Li, Y Liu, Z Liu… - Journal of nanoscience …, 2009 - ingentaconnect.com
Poly (D, L-lactide-co-glycolide)(PLGA) is a biodegradable and biocompatible polymer
material for drug deliver system. The aim of this study is to synthesize drug-loaded PLGA …

Electrospray-based synthesis of fluorescent poly (d, l-lactide-co-glycolide) nanoparticles for the efficient delivery of an anticancer drug and self-monitoring its effect in …

M Chatterjee, R Maity, S Das, N Mahata, B Basu… - Materials …, 2020 - pubs.rsc.org
A novel approach used to synthesize antimetabolite-conjugated and intense blue
fluorescence-emitting smart polymeric nanoparticles is reported for the efficient delivery of …

PLGA nanoparticles stabilized with cationic surfactant: safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat

V Bhardwaj, DD Ankola, SC Gupta, M Schneider… - Pharmaceutical …, 2009 - Springer
Purpose This study was carried out to formulate poly (lactide-co-glycolide)(PLGA)
nanoparticles using a quaternary ammonium salt didodecyl dimethylammonium bromide …

Development of 6-Thioguanine conjugated PLGA nanoparticles through thioester bond formation: Benefits of electrospray mediated drug encapsulation and sustained …

M Chatterjee, N Jaiswal, A Hens, N Mahata… - Materials Science and …, 2020 - Elsevier
Polymeric nanoparticle-based successful delivery of hydrophobic drugs is highly desirable
for its controlled and sustained release at the disease site, which is a challenge with the …

Preparation and characterization of PLGA-β-CD polymeric nanoparticles containing methotrexate and evaluation of their effects on T47D cell line

F Gorjikhah, F Azizi Jalalian, R Salehi… - Artificial cells …, 2017 - Taylor & Francis
Among all cancers that affect women, breast cancer has most mortality rate. It is essential to
attain more safe and efficient anticancer drugs. Recent advances in medical …