Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review

B Zimmerman, B Rypma, G Gratton… - …, 2021 - Wiley Online Library
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

Vascular cognitive impairment, dementia, aging and energy demand. A vicious cycle

A Popa-Wagner, AM Buga, B Popescu… - Journal of neural …, 2015 - Springer
To a great extent, cognitive health depends on cerebrovascular health and a deeper
understanding of the subtle interactions between cerebrovascular function and cognition is …

Regional cerebrovascular reactivity and cognitive performance in healthy aging

SJ Catchlove, TB Parrish, Y Chen… - Journal of …, 2018 - journals.sagepub.com
Cerebrovascular reactivity (CVR) reflects the response of brain blood vessels to vasoactive
stimuli, such as neural activity. The current research assessed age-related changes in …

At the heart of cognitive functioning in aging

A Wåhlin, L Nyberg - Trends in cognitive sciences, 2019 - cell.com
Several neural and non-neural factors contribute to individual differences in cognitive
performance. Here we outline a sequence of vascular events where excessive transfer of …

Hearts and minds: linking vascular rigidity and aerobic fitness with cognitive aging

CJ Gauthier, M Lefort, S Mekary… - Neurobiology of …, 2015 - Elsevier
Human aging is accompanied by both vascular and cognitive changes. Although arteries
throughout the body are known to become stiffer with age, this vessel hardening is believed …

Endothelium-dependent control of cerebrovascular functions through age: exercise for healthy cerebrovascular aging

V Bolduc, N Thorin-Trescases… - American Journal of …, 2013 - journals.physiology.org
Cognitive performances are tightly associated with the maximal aerobic exercise capacity,
both of which decline with age. The benefits on mental health of regular exercise, which …

Age-related changes in cerebrovascular reactivity and their relationship to cognition: a four-year longitudinal study

SL Peng, X Chen, Y Li, KM Rodrigue, DC Park, H Lu - Neuroimage, 2018 - Elsevier
Although cerebrovascular factors are the second leading cause of cognitive impairment and
dementia in elderly, the precise spatial and temporal trajectories of vascular decline in aging …

Benefits of exercise training on cerebrovascular and cognitive function in ageing

ES Bliss, RHX Wong, PRC Howe… - Journal of Cerebral …, 2021 - journals.sagepub.com
Derangements in cerebrovascular structure and function can impair cognitive performance
throughout ageing and in cardiometabolic disease states, thus increasing dementia risk …

Cerebral hemodynamics of the aging brain: risk of Alzheimer disease and benefit of aerobic exercise

T Tarumi, R Zhang - Frontiers in physiology, 2014 - frontiersin.org
Alzheimer disease (AD) and cerebrovascular disease often coexist with advanced age.
Mounting evidence indicates that the presence of vascular disease and its risk factors …

[HTML][HTML] Vascular cognitive impairment–Past, present, and future challenges

A Badji, J Youwakim, A Cooper, E Westman… - Ageing Research …, 2023 - Elsevier
Vascular cognitive impairment (VCI) is a lifelong process encompassing a broad spectrum of
cognitive disorders, ranging from subtle or mild deficits to prodromal and fully developed …