Enzymatic synthesis that is commenced by the sugar nucleotide regeneration system
(SNRS) protocol can minimize 1) the consumption of exorbitant sugar nucleotides, 2) the …

Abstract Sialosides containing (oligo-) N-acetyllactosamine (LacNAc, Galβ (1, 4) GlcNAc) as
core structure are known to serve as ligands for Siglecs. However, the role of tandem inner …

Quantification, characterization and biofunctional studies of N-glycans on proteins remain
challenging tasks due to the complexity, diversity and low abundance of these glycans. The …

We have investigated the consequences of introducing a bisecting GlcNAc moiety into
biantennary N‐glycans. Computational analysis of glycan conformation with prolonged …

Glycosyl phosphates are known as versatile donors for the synthesis of complex
oligosaccharides both chemically and enzymatically. Herein, we report the stereoselective …

N-Linked glycopeptides have highly diverse structures in nature. Herein, we describe the
first synthesis of rare multi-antennary N-glycan bearing glycan chains on 6-OH of both α1, 6 …

Glycosylation of proteins is a key function of the biosynthetic‐secretory pathway in the
endoplasmic reticulum (ER) and Golgi apparatus. Glycosylated proteins play a crucial role in …

N-Acetylhexosamine oligosaccharides terminated with GalNAc act as selective ligands of
galectin-3, a biomedically important human lectin. Their synthesis can be accomplished by β …

Synthetic carbohydrate receptors (SCRs) that selectively recognize cell‐surface glycans
could be used for detection, drug delivery, or as therapeutics. Here we report the synthesis …

A comprehensive method for the construction of a high‐mannose‐type glycan library by
systematic chemo‐enzymatic trimming of a single Man9‐based precursor was developed. It …