Motivation With the discovery of cell-free fetal DNA in maternal blood, the demand for non-
invasive prenatal testing (NIPT) has been increasing. To obtain reliable NIPT results, it is …

Background With the speedy development of sequencing technologies, noninvasive
prenatal testing (NIPT) has been widely applied in clinical practice for testing for fetal …

Cell-free fetal DNA fraction (FF) in maternal plasma is a key parameter affecting the
performance of noninvasive prenatal testing (NIPT). Accurate quantitation of FF plays a …

An important factor in quality control of non-invasive prenatal screening (NIPS) or testing
(NIPT) is a sufficient percentage of fetal DNA to avoid false-negative results. Here we …

Background Molecular size determination of circulating free fetal DNA in maternal plasma is
an important detection method for noninvasive prenatal testing (NIPT). The fetal DNA …

The discovery of circulating cell-free fetal DNA has profoundly transformed the landscape of
noninvasive prenatal testing (NIPT) and rapidly found its way into global clinical …

Objective Non‐invasive prenatal testing (NIPT) based on fetal cells in maternal blood has
the advantage over NIPT based on circulating cell‐free fetal DNA in that there is no …

Background Noninvasive prenatal testing (NIPT) is one of the most commonly employed
clinical measures for screening of fetal aneuploidy. Fetal Fraction (ff) has been …

The discovery of cell-free fetal DNA molecules in plasma of pregnant women has created a
paradigm shift in noninvasive prenatal testing (NIPT). Circulating cell-free DNA in maternal …

Noninvasive prenatal testing (NIPT) consists of determining fetal aneuploidies by quantifying
copy number alteration from the sequencing of cell-free DNA (cfDNA) from maternal blood …