The gut microbiota in multiple sclerosis varies with disease activity

F Thirion, F Sellebjerg, Y Fan, L Lyu, TH Hansen… - Genome medicine, 2023 - Springer
Background Multiple sclerosis is a chronic immune-mediated disease of the brain and spinal
cord resulting in physical and cognitive impairment in young adults. It is hypothesized that a …

The gut microbiome in multiple sclerosis: a potential therapeutic avenue

TO Kirby, J Ochoa-Repáraz - Medical Sciences, 2018 - mdpi.com
Recently, there has been a substantial increase in the number of studies focused upon
connecting the gut microbiome with cases of central nervous system (CNS) autoimmunity …

[HTML][HTML] The role of the gut microbiome in multiple sclerosis risk and progression: towards characterization of the “MS microbiome”

AK Pröbstel, SE Baranzini - Neurotherapeutics, 2018 - Elsevier
Multiple sclerosis (MS) is the prototypic complex disease, in which both genes and the
environment contribute to its pathogenesis. To date,> 200 independent loci across the …

Gut microbiome variation is associated to Multiple Sclerosis phenotypic subtypes

T Reynders, L Devolder… - Annals of clinical …, 2020 - Wiley Online Library
Objective Multiple sclerosis (MS) is a heterogenous, inflammatory disease of the central
nervous system. Microbiota alterations in MS versus healthy controls (HC) are observed, but …

Alterations of host-gut microbiome interactions in multiple sclerosis

C Cantoni, Q Lin, Y Dorsett, L Ghezzi, Z Liu, Y Pan… - …, 2022 - thelancet.com
Background Multiple sclerosis (MS) has a complex genetic, immune and metabolic
pathophysiology. Recent studies implicated the gut microbiome in MS pathogenesis …

Combined therapies to treat complex diseases: The role of the gut microbiota in multiple sclerosis

L Calvo-Barreiro, H Eixarch, X Montalban… - Autoimmunity reviews, 2018 - Elsevier
The commensal microbiota has emerged as an environmental risk factor for multiple
sclerosis (MS). Studies in experimental autoimmune encephalomyelitis (EAE) models have …

Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course

X Zhou, R Baumann, X Gao, M Mendoza, S Singh… - Cell, 2022 - cell.com
Changes in gut microbiota have been associated with several diseases. Here, the
International Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of …

The role of the gut microbiota in multiple sclerosis

J Correale, R Hohlfeld, SE Baranzini - Nature Reviews Neurology, 2022 - nature.com
During the past decade, research has revealed that the vast community of micro-organisms
that inhabit the gut—known as the gut microbiota—is intricately linked to human health and …

[HTML][HTML] Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls

J Chen, N Chia, KR Kalari, JZ Yao, M Novotna… - Scientific reports, 2016 - nature.com
Multiple sclerosis (MS) is an immune-mediated disease, the etiology of which involves both
genetic and environmental factors. The exact nature of the environmental factors …

The gut microbiome in multiple sclerosis

DW Mielcarz, LH Kasper - Current treatment options in neurology, 2015 - Springer
Opinion statement The gut microbiome is made up of a wide range of (chiefly) bacterial
species that colonize the small and large intestine. The human gut microbiome contains a …