Exploration of bioengineered scaffolds composed of thermo-responsive polymers for drug delivery in wound healing

L Castillo-Henríquez, J Castro-Alpízar… - International Journal of …, 2021 - mdpi.com
Innate and adaptive immune responses lead to wound healing by regulating a complex
series of events promoting cellular cross-talk. An inflammatory response is presented with its …

Advances in thermosensitive polymer-grafted platforms for biomedical applications

PN Le, CK Huynh, NQ Tran - Materials Science and Engineering: C, 2018 - Elsevier
Studies on “smart” polymeric material performing environmental stimuli such as temperature,
pH, magnetic field, enzyme and photo-sensation have recently paid much attention to …

Smart Delivery Platform Using Core–Shell Nanofibers for Sequential Drug Release in Wound Healing

B Singh, J Kim, N Shukla, J Lee, K Kim… - ACS Applied Bio …, 2023 - ACS Publications
An effective approach to accelerating wound healing is through a smart delivery platform
that releases drugs according to the needs of different healing periods. With the growing …

Thermoresponsive polymers for biomedical applications

MA Ward, TK Georgiou - Polymers, 2011 - mdpi.com
Thermoresponsive polymers are a class of “smart” materials that have the ability to respond
to a change in temperature; a property that makes them useful materials in a wide range of …

Thermo-responsive polymers: Applications of smart materials in drug delivery and tissue engineering

M Sponchioni, UC Palmiero, D Moscatelli - Materials Science and …, 2019 - Elsevier
Synthetic polymers are attracting great attention in the last decades for their use in the
biomedical field as nanovectors for controlled drug delivery, hydrogels and scaffolds …

Thermo-sensitive polymers in medicine: A review

P Zarrintaj, M Jouyandeh, MR Ganjali… - European Polymer …, 2019 - Elsevier
A wide variety of smart polymer systems such as thermosensitive polymers (TSPs) have
been developed and applied mimicking nature. TSPs are a class of macromolecules that …

Bioresponsive hybrid nanofibers enable controlled drug delivery through glass transition switching at physiological temperature

F Pan, A Amarjargal, S Altenried, M Liu… - ACS Applied Bio …, 2021 - ACS Publications
To avoid excessive usage of antibiotics and antimicrobial agents, smart wound dressings
permitting controlled drug release for treatment of bacterial infections are highly desired. In …

3D printing of thermoresponsive hydrogel laden with an antimicrobial agent towards wound healing applications

M Nizioł, J Paleczny, A Junka, A Shavandi… - Bioengineering, 2021 - mdpi.com
Thermoresponsive hydrogel-based wound dressings with an incorporated antimicrobial
agent can be fabricated employing 3D printing technology. A novel printable ink containing …

Biodegradable elastic nanofibrous platforms with integrated flexible heaters for on-demand drug delivery

A Tamayol, A Hassani Najafabadi, P Mostafalu… - Scientific reports, 2017 - nature.com
Delivery of drugs with controlled temporal profiles is essential for wound treatment and
regenerative medicine applications. For example, bacterial infection is a key challenge in …

Smart biomaterial-based systems for intrinsic stimuli-responsive chronic wound management

PM Alves, CC Barrias, P Gomes, MCL Martins - Materials Today Chemistry, 2021 - Elsevier
Skin chronic wounds are associated with a state of persistent inflammation and often with
infection, originating a specific microenvironment characterized by increased temperature …