Approximately 13% of the human genome can fold into non-canonical (non-B) DNA
structures (eg G-quadruplexes, Z-DNA, etc.), which have been implicated in vital cellular …

Somatic mutations show variation in density across cancer genomes. Previous studies have
shown that chromatin organization and replication time domains are correlated with, and …

We investigated substitution patterns and neighboring-nucleotide effects for 2,576,903
single nucleotide polymorphisms (SNPs) publicly available through the National Center for …

Repetitive DNA motifs may fold into non‐B DNA structures, including cruciforms/hairpins,
triplexes, slipped conformations, quadruplexes, and left‐handed Z‐DNA, thereby …

Point mutation rates in exons (synonymous sites) and noncoding (introns and intergenic)
regions are generally assumed to be the same. However, comparative sequence analyses …

Repetitive elements in the human genome, once considered 'junk DNA', are now known to
adopt more than a dozen alternative (that is, non-B) DNA structures, such as self-annealed …

Neutral nucleotide substitutions occur at varying rates along genomes, and it remains a
major issue to unravel the mechanisms that cause these variations and to analyze their …

Repetitive DNA motifs are abundant in the genomes of various species and have the
capacity to adopt non-canonical (ie, non-B) DNA structures. Several non-B DNA structures …

The pattern of 20,200 point substitutions in the 16 unique neighbor-pair environments has
been determined from aligned gene/pseudogene sequences in the current database of …

Genes that have experienced accelerated evolutionary rates on the human lineage during
recent evolution are candidates for involvement in human-specific adaptations. To …