[HTML][HTML] Effectiveness and safety of apixaban vs. warfarin in venous thromboembolism patients with obesity and morbid obesity

A Cohen, J Sah, T Lee, L Rosenblatt… - Journal of Clinical …, 2021 - mdpi.com
This study integrated 5 United States healthcare claims databases to evaluate the risk of
recurrent venous thromboembolism (VTE) and major bleeding (MB) among VTE patients …

Multi‐center retrospective study evaluating the efficacy and safety of apixaban versus warfarin for treatment of venous thromboembolism in patients with severe …

A Crouch, TH Ng, D Kelley, T Knight… - … : The Journal of …, 2022 - Wiley Online Library
Abstract Study Objective Direct oral anticoagulants are the standard of care for venous
thromboembolism (VTE) treatment. These agents are recommended regardless of patient …

[HTML][HTML] Efficacy, safety, and exposure of apixaban in patients with high body weight or obesity and venous thromboembolism: insights from AMPLIFY

AT Cohen, S Pan, W Byon, BS Ilyas, T Taylor… - Advances in Therapy, 2021 - Springer
Introduction As a result of limited clinical data, guidelines do not recommend the use of non-
vitamin K antagonist oral anticoagulants in patients who weigh> 120 kg or have a body …

Apixaban and rivaroxaban in obese patients treated for venous thromboembolism: drug levels and clinical outcomes

A Ballerie, RN Van, K Lacut, H Galinat, C Rousseau… - Thrombosis research, 2021 - Elsevier
Background Direct oral anticoagulants (DOAC) use remains challenging in obese patients
treated for Venous-Thrombo-Embolism (VTE) due to the paucity of prospective and …

[HTML][HTML] Apixaban is safe and effective in morbidly obese patients: a retrospective analysis of 390 patients with BMI≥ 40

Y Choi, M Kushnir, HH Billett - Blood, 2017 - Elsevier
Background: In patients with venous thromboembolism (VTE), warfarin had been considered
standard of care until the new direct oral anticoagulants (DOACs) were developed. Studies …

[HTML][HTML] Rivaroxaban versus warfarin treatment among morbidly obese patients with venous thromboembolism: comparative effectiveness, safety, and costs

AC Spyropoulos, V Ashton, YW Chen, B Wu… - Thrombosis research, 2019 - Elsevier
Introduction Limited data exist on direct-acting oral anticoagulants in morbidly obese
patients with venous thromboembolism (VTE). We compared clinical and health/economic …

Effectiveness and safety of rivaroxaban versus warfarin in obese patients with acute venous thromboembolism: analysis of electronic health record data

OS Costa, J Beyer-Westendorf, V Ashton… - Journal of Thrombosis …, 2021 - Springer
There is limited data evaluating clinical outcomes of rivaroxaban versus warfarin in obese
patients with venous thromboembolism (VTE). Our objective was to evaluate the …

Management of venous thromboembolism in morbid obesity with rivaroxaban or warfarin

P Weaver, TH Ng, T Breeden… - Annals of …, 2022 - journals.sagepub.com
Background Rivaroxaban is a first-line option for the management of venous
thromboembolism (VTE). However, limited data are available regarding its effectiveness in …

[HTML][HTML] The use of direct oral anticoagulants in the management of venous thromboembolism in patients with obesity

M Younis, A Elkaryoni, GW Williams, I Jakhar, S Suman… - Cureus, 2020 - ncbi.nlm.nih.gov
Methods We utilized the Health Facts Center National Data Warehouse (Cerner) to perform
a retrospective analysis of patients with VTE (acute deep venous thrombosis (DVT) or …

[HTML][HTML] Safety and effectiveness of apixaban compared with warfarin among clinically-relevant subgroups of venous thromboembolism patients in the United States …

JD Guo, P Hlavacek, L Rosenblatt, A Keshishian… - Thrombosis research, 2021 - Elsevier
Background The AMPLIFY trial found significantly lower major bleeding (MB) and similar
recurrent venous thromboembolism (VTE) risks associated with apixaban vs warfarin among …