Effect of Copper and Zinc Ions on Biochemical and Molecular Characteristics of Calcium Oxalate Renal Stones: a Controlled Clinical Study

SAY Taha, AA Shokeir, WI Mortada, A Awadalla… - … Trace Element Research, 2024 - Springer
Contradictory results are existed in the literature regarding the impact of trace elements on
the pathogenesis of calcium oxalate (CaOx) stone patients. Therefore, the aim of our study …

Serum, urinary and stone zinc, iron, magnesium and copper levels in idiopathic calcium oxalate stone patients

IH Atakan, M Kaplan, G Seren, T Aktoz, H Gül… - International urology and …, 2007 - Springer
Many theories have been put forward to explain the mechanism of stone formation and
growth. The aim of this study was to investigate the urinary, serum and stone levels of zinc …

Calcium oxalate monohydrate binding protein: a diagnostic biomarker for calcium oxalate kidney stone formers

D Asokan, P Kalaiselvi, S Muhammed Farooq… - Urological …, 2004 - Springer
Urinary oxalate is a biomarker for calcium oxalate kidney stone disease; however, its assay
is insensitive and nonspecific. Calcium oxalate monohydrate (COM) binding protein (45 …

Calcium oxalate stone disease: role of lipid peroxidation and antioxidants

R Selvam - Urological research, 2002 - Springer
Membrane injury facilitated the fixation of calcium oxalate crystals and subsequent growth
into kidney stones. Oxalate-induced membrane injury was mediated by lipid peroxidation …

Renal tubular cell damage and oxidative stress in renal stone patients and the effect of potassium citrate treatment

K Tungsanga, P Sriboonlue, P Futrakul, C Yachantha… - Urological …, 2005 - Springer
Our objective was to evaluate the oxidative stress and renal tubular cell damage in patients
who have renal stones compared to normal subjects. The patients were re-evaluated after 1 …

Heavy metal components in blood and urinary stones of urolithiasis patients

Y Yen, B Cheng, C Chan, C Lin, H Chen - Biological trace element …, 2018 - Springer
Lifestyle, food intake, and exposure to chemicals are potential risk factors for the
development of calcium urolithiasis. Pb, Cd, and Hg have been proved to cause renal …

Role of urinary zinc and copper on calcium oxalate stone formation

T Ozgurtas, G Yakut, M Gulec, M Serdar… - Urologia …, 2004 - karger.com
Introduction: It is considered that many factors may play a role in urolithiasis. Experimental
and clinical studies have shown that zinc has an inhibitory effect on urolithiasis. Materials …

[HTML][HTML] Losartan ameliorates calcium oxalate-induced elevation of stone-related proteins in renal tubular cells by inhibiting NADPH oxidase and oxidative stress

B Qin, Q Wang, Y Lu, C Li, H Hu, J Zhang… - … Medicine and Cellular …, 2018 - hindawi.com
Calcium oxalate (CaOx) is the most common type of urinary stone. Increase of ROS and
NADPH oxidase gives rise to inflammation and injury of renal tubular cells, which promotes …

Reactive oxygen species as the molecular modulators of calcium oxalate kidney stone formation: evidence from clinical and experimental investigations

SR Khan - The Journal of urology, 2013 - auajournals.org
Purpose: Idiopathic calcium oxalate kidney stones form while attached to Randall plaques,
the subepithelial deposits on renal papillary surfaces. Plaque formation and growth …

Uric acid: an abettor or protector in calcium oxalate urolithiasis? Biochemical study in stone formers

S Srinivasan, P Kalaiselvi, R Sakthivel, V Pragasam… - Clinica Chimica …, 2005 - Elsevier
BACKGROUND: Free radical induced renal damage leads to crystal retention and formation
of large stones. However, the scenario behind uric acid (UA) stone formation is still a …