Counter-current fractionation-assisted and bioassay-guided separation of active compounds from cranberry and their interaction with α-glucosidase

H Xue, J Tan, X Zhu, Q Li, J Tang, X Cai - LWT, 2021 - Elsevier
An effective method for the selection of active compounds from cranberry based on counter-
current fractionation and bioassay-guided separation was established. Cranberry extract …

Counter-current fractionation-assisted bioassay-guided separation of active compound from blueberry and the interaction between the active compound and α …

H Xue, X Zhu, J Tan, L Fan, Q Li, J Tang, X Cai - Foods, 2021 - mdpi.com
An efficient strategy for the selection of active compounds from blueberry based on counter-
current fractionation and bioassay-guided separation was established in this study …

Screening and characterization of potential α-glucosidase inhibitors from Cercis chinensis Bunge fruits using ultrafiltration coupled with HPLC-ESI-MS/MS

Y Hong, X Liao, Z Chen - Food Chemistry, 2022 - Elsevier
Abstract A more accurate HPLC-MS screening method combining functional enzyme assay
and affinity ultrafiltration screening assay was developed and applied for the screening of …

α-Glucosidase inhibitors from Chinese bayberry (Morella rubra Sieb. et Zucc.) fruit: molecular docking and interaction mechanism of flavonols with different B-ring …

Y Liu, L Zhan, C Xu, H Jiang, C Zhu, L Sun, C Sun… - RSC advances, 2020 - pubs.rsc.org
Inhibition of α-glucosidase alleviates postprandial high glycemic levels in diabetic or
prediabetic population. In Chinese bayberry fruit, myricetin, quercetin and kaempferol are …

Comparison of inhibitory activities and mechanisms of five mulberry plant bioactive components against α-glucosidase

H He, YH Lu - Journal of agricultural and food chemistry, 2013 - ACS Publications
The α-glucosidase inhibitory effects of five bioactive components, namely 1-
deoxynojirimycin, cyanidin-3-glucoside, cyanidin-3-rutinoside, resveratrol and …

Screening and identification of α-glucosidase inhibitors from Cyclocarya paliurus leaves by ultrafiltration coupled with liquid chromatography-mass spectrometry and …

YJ Li, GZ Wan, FC Xu, ZH Guo, J Chen - Journal of Chromatography A, 2022 - Elsevier
Cyclocarya paliurus, as an important edible and medicinal product, has shown a good
prospect in the prevention of diabetes mellitus (DM). However, it is unclear which active …

[HTML][HTML] Inhibitory kinetics and mechanism of active compounds in green walnut husk against α-glucosidase: Spectroscopy and molecular docking analyses

H Shen, J Wang, J Ao, Y Cai, M Xi, Y Hou, M Li, A Luo - Lwt, 2022 - Elsevier
Inhibiting the activity of α-glucosidase is considered an effective strategy to regulate blood
sugar levels and manage food-linked hyperglycemia. Green walnut husk (GWH) is the main …

α-Glucosidase inhibitors from brown rice bound phenolics extracts (BRBPE): Identification and mechanism

C Ye, R Zhang, L Dong, J Chi, F Huang, L Dong… - Food chemistry, 2022 - Elsevier
Brown rice bound phenolics extracts (BRBPE) have been reported to possess α-glucosidase
inhibitory effects, the specific enzyme inhibitors involved in this process were unknown …

Bioactivity-guided separation of potential α-glycosidase inhibitor from clerodendranthus spicatus based on HSCCC coupled with molecular docking

C Zhu, H Niu, A Nie, M Bian - Scientific Reports, 2021 - nature.com
Clerodendranthus Spicatus is a traditional Dais medi-edible plant and it has been proven to
have good blood glucose-lowering efficacy. However, the material basis of …

Inhibitory mechanism of novel allosteric inhibitor, Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves proanthocyanidins against α-glucosidase

M Wang, J Jiang, J Tian, S Chen, X Ye, Y Hu… - Journal of functional …, 2019 - Elsevier
Abstract α-Glucosidase is a key enzyme related to starch digestion and type-2 diabetes. In
the present study, the inhibition effect and the underlying mechanism of Chinese bayberry …