Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

The pathogenesis and clinical features of diabetic cardiomyopathy have been well-studied
in the past decade, but effective approaches to prevent and treat this disease are limited …

Diabetes mellitus increases the risk of heart failure independently of underlying coronary
artery disease, and many believe that diabetes leads to cardiomyopathy. The underlying …

Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …

Type 2 diabetes is a redox disease. Oxidative stress and chronic inflammation induce a
switch of metabolic homeostatic set points, leading to glucose intolerance. Several diabetes …

Diabetes is a serious public health problem. Improvements in the treatment of noncardiac
complications from diabetes have resulted in heart disease becoming a leading cause of …

The diabetic heart is characterized by metabolic disturbances that are often accompanied by
local inflammation, oxidative stress, myocardial fibrosis, and cardiomyocyte apoptosis …

Despite being first described 45 years ago, the existence of a distinct diabetic
cardiomyopathy remains controversial. Nonetheless, it is widely accepted that the diabetic …

Diabetes is a chronic metabolic disease that is increasing in prevalence and causes many
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …

Heart failure and related morbidity and mortality are increasing at an alarming rate, in large
part, because of increases in aging, obesity, and diabetes mellitus. The clinical outcomes …