Although AMP-activated protein kinase (AMPK) is involved in regulating carbohydrate and
lipid metabolism, activated AMPK also plays an anti-inflammatory role in many cell …

AMP-activated protein kinase (AMPK) is activated by increases in the intracellular AMP-to-
ATP ratio and plays a central role in cellular responses to metabolic stress. Although …

Acute lung injury (ALI) or its more severe form, known as acute respiratory distress
syndrome (ARDS), is characterized by an initial exudative phase, expression of …

Dysregulation of alveolar macrophage activation has been recognized as the major
mechanism in the pathogenesis of acute lung injury. The aim of the present study was to …

Acute lung injury (ALI) is mediated by an early proinflammatory response resulting from
either a direct or indirect insult to the lung mediating neutrophil infiltration and consequent …

Alterations in metabolic and bioenergetic homeostasis contribute to sepsis-mediated organ
injury. However, how AMP-activated protein kinase (AMPK), a major sensor and regulator of …

Background Although in vitro studies have determined that the activation of mitogen-
activated protein (MAP) kinases is crucial to the activation of transcription factors and …

Herein, we demonstrate a role of AMP-activated protein kinase (AMPK) as a potent
counterregulator of inflammatory signaling pathways in macrophages. Stimulation of …

Adenosine monophosphate-activated protein (AMP)-activated kinase (AMPK) is a highly
conserved kinase that plays a key role in energy homeostasis. Activation of AMPK was …

Mitogen-activated protein kinases (MAPKs) play a critical role in inflammation. Although
activation of MAPK in inflammatory cells has been studied extensively, much less is known …