[HTML][HTML] Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis

TS Dutt, BR Karger, A Fox, N Youssef, R Dadhwal… - Cell reports, 2022 - cell.com
Summary Bacille Calmette-Guerin (BCG) is the only licensed vaccine against
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB) disease …

[HTML][HTML] Characterizing the BCG Induced Macrophage and Neutrophil Mechanisms for Defense Against Mycobacterium tuberculosis

TE Bickett, J McLean, E Creissen, L Izzo… - Frontiers in …, 2020 - frontiersin.org
The live attenuated Mycobacterium bovis strain, Bacille Calmette Guérin (BCG) is a potent
innate immune stimulator. In the C57BL/6 mouse model of tuberculosis, BCG vaccination …

[HTML][HTML] Non-tuberculous mycobacteria interference with BCG-current controversies and future directions

D Verma, ED Chan, DJ Ordway - Vaccines, 2020 - mdpi.com
The global tuberculosis (TB) epidemic caused by the bacterial pathogen Mycobacterium
tuberculosis (M. tb) continues unabated. The Mycobacterium bovis bacillus Calmette–Guérin …

[HTML][HTML] Non-tuberculous mycobacteria have diverse effects on BCG efficacy against Mycobacterium tuberculosis

HC Poyntz, E Stylianou, KL Griffiths, L Marsay… - Tuberculosis, 2014 - Elsevier
Summary The efficacy of Bacillus Calmette-Guerin (BCG) vaccination in protection against
pulmonary tuberculosis (TB) is highly variable between populations. One possible …

Nontuberculous mycobacteria and heterologous immunity to tuberculosis

JA Shah, CS Lindestam Arlehamn… - The Journal of …, 2019 - academic.oup.com
Abstract Development of an improved tuberculosis (TB) vaccine is a high worldwide public
health priority. Bacillus Calmette-Guerin (BCG), the only licensed TB vaccine, provides …

[HTML][HTML] BCG Induces Protection against Mycobacterium tuberculosis Infection in the Wistar Rat Model

A Singhal, V Mathys, M Kiass, C Creusy, B Delaire… - PLoS …, 2011 - journals.plos.org
Our understanding of the correlation of Mycobacterium bovis Bacille Calmette-Guerin (BCG)-
mediated immune responses and protection against Mycobacterium tuberculosis (Mtb) …

Pulmonary BCG induces lung-resident macrophage activation and confers long-term protection against tuberculosis

E Mata, R Tarancon, C Guerrero, E Moreo… - Science …, 2021 - science.org
Bacillus Calmette-Guerin (BCG) is an attenuated bacterial vaccine used to protect against
Mycobacterium tuberculosis (Mtb) in regions where infections are highly prevalent. BCG is …

[HTML][HTML] The BCGΔBCG1419c vaccine candidate reduces lung pathology, IL-6, TNF-α, and IL-10 during chronic TB infection

MA Flores-Valdez, C Pedroza-Roldán… - Frontiers in …, 2018 - frontiersin.org
Mycobacterium tuberculosis (M. tuberculosis), the causative agent of human tuberculosis
(TB), is estimated to be harbored by up to 2 billion people in a latent TB infection (LTBI) …

[HTML][HTML] Repeated aerosolized-boosting with gamma-irradiated Mycobacterium bovis BCG confers improved pulmonary protection against the hypervirulent …

SB Cha, WS Kim, JS Kim, H Kim, KW Kwon, SJ Han… - PloS one, 2015 - journals.plos.org
Mycobacterium bovis bacillus Calmette-Guerin (BCG), the only licensed vaccine, shows
limited protection efficacy against pulmonary tuberculosis (TB), particularly hypervirulent …

[HTML][HTML] Assessing vaccine-mediated protection in an ultra-low dose Mycobacterium tuberculosis murine model

CR Plumlee, HW Barrett, DE Shao, KA Lien… - Plos …, 2023 - journals.plos.org
Despite widespread immunization with Bacille-Calmette-Guérin (BCG), the only currently
licensed tuberculosis (TB) vaccine, TB remains a leading cause of mortality globally. There …