For over 30 years a phospholipase C enzyme called alpha-toxin was thought to be the key
virulence factor in necrotic enteritis caused by Clostridium perfringens. However, using a …

A novel toxin, NetB, has recently been identified in virulent avian Clostridium perfringens
isolates and shown to be an essential virulence factor in a clinical necrotic enteritis isolate …

The Clostridium perfringens necrotic enteritis toxin B, NetB, was recently proposed as a new
key virulence factor for the development of necrotic enteritis (NE) in broilers. The aim of the …

Necrotic enteritis (NE) is a devastating enteric disease caused by Clostridium perfringens
type A/G that impacts the global poultry industry by compromising the performance, health …

Clostridium perfringens-induced necrotic enteritis and related subclinical disease have
become economically significant problems for the broiler industry. Fortunately, scientific …

Clostridium perfringens is the primary causative agent of avian necrotic enteritis. Our
understanding of the pathogenesis of this economically important disease has been …

The Clostridium perfringens necrotic enteritis B-like toxin (NetB) is a recently discovered
member of the β-barrel pore-forming toxin family and is produced by a subset of avian C …

Necrotic enteritis (NE) caused by Clostridium perfringens has emerged as an important
disease associated with major economic losses in the poultry industry worldwide. The ban …

Withdrawal of antimicrobial growth promoters and ionophore coccidiostats has been
accompanied by a resurgence in incidence of necrotic enteritis (NE), a severe Clostridium …

A previously unknown pore forming toxin, called NetB toxin, which is produced by some
Australian strains of Clostridium perfringens has recently been reported. This toxin was …