Background Chemotherapy after transurethral resection is commonly recommended for
bladder cancer. However, studies have shown that chemotherapy solely can hardly …

In this study, gold nanorods (GNRs) were incorporated into the hydrogel networks formed by
the copolymerization of N-isopropylacrylamide (NIPAm) and methacrylated poly-β …

Systemic administration of platinum-based drugs has obvious limitations in the treatment of
advanced bladder cancer (BC) owing to lower tumor accumulation and uncontrolled release …

The purpose of this paper is to develop a pH/thermal sensitive nanohydrogel composite for
in situ injection and to achieve an enhanced chemo-photothermal synergistic antitumor …

Background Chemotherapy is a standard cancer treatment which uses anti-cancer drugs to
destroy or slow the growth of cancer cells. However, chemotherapy has limited therapeutic …

Bladder cancer is one of the most common malignant tumors in the urinary system
worldwide. The poor permeability and uncontrollable release of drug and hypoxia of tumor …

Traditional hydrogels have drawbacks such as surgical implantation, large wound surfaces,
and uncontrollable drug release during tumor treatment. In this paper, targeted …

Photodynamic therapy (PDT) efficacy has been severely limited by the hypoxia in tumor
microenvironment. A multitherapy modality was developed, integrating the advantages of …

This study reports on an intelligent composite hydrogel with both pH-dependent drug
release in a cancer environment and heat generation based on NIR laser exposure, for the …

Multifunctional nanoparticles are of significant importance for synergistic multimodal
antitumor activity. Herein, zinc oxide (ZnO) was used as pH-sensitive nanoparticles for …