Chromatin-sensitive cryptic promoters encode alternative protein isoforms in yeast

W Wei, BP Hennig, J Wang, Y Zhang, I Piazza… - bioRxiv, 2018 - biorxiv.org
Cryptic transcription is widespread and generates a heterogeneous group of RNA
molecules of unknown function. To improve our understanding of cryptic transcription, we …

Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast

W Wei, BP Hennig, J Wang, Y Zhang, I Piazza… - Genome …, 2019 - genome.cshlp.org
Cryptic transcription is widespread and generates a heterogeneous group of RNA
molecules of unknown function. To improve our understanding of cryptic transcription, we …

Bidirectional terminators in Saccharomyces cerevisiae prevent cryptic transcription from invading neighboring genes

N Uwimana, P Collin, C Jeronimo… - Nucleic acids …, 2017 - academic.oup.com
Transcription can be quite disruptive for chromatin so cells have evolved mechanisms to
preserve chromatin integrity during transcription, thereby preventing the emergence of …

[HTML][HTML] Chromatin-and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome

V Cheung, G Chua, NN Batada, CR Landry… - PLoS …, 2008 - journals.plos.org
Previous studies in Saccharomyces cerevisiae have demonstrated that cryptic promoters
within coding regions activate transcription in particular mutants. We have performed a …

[图书][B] Investigation of transcription initiation from cryptic promoter sites in Saccharomyces cerevisiae

V Cheung - 2008 - search.proquest.com
Previous studies in Saccharomyces cerevisiae have shown that mutations in SPT6, SPT16,
SET2, and other genes encoding particular chromatin and transcription factors cause the …

Core promoter activity contributes to chromatin-based regulation of internal cryptic promoters

BB Lee, H Woo, MK Lee, SJ Youn, S Lee… - Nucleic acids …, 2021 - academic.oup.com
Abstract During RNA polymerase II (RNA Pol II) transcription, the chromatin structure
undergoes dynamic changes, including opening and closing of the nucleosome to enhance …

[HTML][HTML] Repression of divergent noncoding transcription by a sequence-specific transcription factor

ACK Wu, H Patel, M Chia, F Moretto, D Frith… - Molecular cell, 2018 - cell.com
Many active eukaryotic gene promoters exhibit divergent noncoding transcription, but the
mechanisms restricting expression of these transcripts are not well understood. Here, we …

Pervasive transcription: a controlled risk

T Villa, O Porrua - The FEBS Journal, 2023 - Wiley Online Library
Transcriptome‐wide interrogation of eukaryotic genomes has unveiled the pervasive nature
of RNA polymerase II transcription. Virtually, any DNA region with an accessible chromatin …

Noncanonical transcript forms in yeast and their regulation during environmental stress

OK Yoon, RB Brem - Rna, 2010 - rnajournal.cshlp.org
Surveys of transcription in many organisms have observed widespread expression of RNAs
with no known function, encoded within and between canonical coding genes. The search to …

Widespread bidirectional promoters are the major source of cryptic transcripts in yeast

H Neil, C Malabat, Y d'Aubenton-Carafa, Z Xu… - Nature, 2009 - nature.com
Pervasive and hidden transcription is widespread in eukaryotes,,,, but its global level, the
mechanisms from which it originates and its functional significance are unclear. Cryptic …