[HTML][HTML] MALAT1/miR-15b-5p/MAPK1 mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic heart disease via mTOR signaling …

Y Zhu, T Yang, J Duan, N Mu, T Zhang - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Objective: Present study focused on the influence of lncRNA MALAT1 on coronary
atherosclerotic heart disease (CAD) by regulating miR-15b-5p/MAPK1 and mTOR signaling …

Ox-LDL-induced lncRNA MALAT1 promotes autophagy in human umbilical vein endothelial cells by sponging miR-216a-5p and regulating Beclin-1 expression

K Wang, C Yang, J Shi, T Gao - European Journal of Pharmacology, 2019 - Elsevier
Metastasis associated lung adenocarcinoma transcript 1 (MALAT1) has been validated as a
potent protective agent of Atherosclerosis (AS). Here, we explored the molecular mechanism …

The suppression of ox-LDL-induced inflammatory cytokine release and apoptosis of HCAECs by long non-coding RNA-MALAT1 via regulating microRNA-155/SOCS1 …

S Li, Y Sun, L Zhong, Z Xiao, M Yang, M Chen… - Nutrition, Metabolism …, 2018 - Elsevier
Background Atherosclerosis is a chronic inflammatory disease. Accumulating evidence
suggests that long non-coding RNAs (lncRNAs) and microRNAs have emerged as critical …

[HTML][HTML] Long non‑coding RNA MALAT1 regulates cholesterol accumulation in ox‑LDL‑induced macrophages via the microRNA‑17‑5p/ABCA1 axis

L Liu, L Tan, J Yao, L Yang - Molecular medicine …, 2020 - spandidos-publications.com
Atherosclerosis (AS), a major cause of cardiovascular disease, has developed into a serious
challenge to the health system. The long non‑coding RNA (lncRNA) metastasis associated …

Long noncoding RNA MALAT1 promotes cardiomyocyte apoptosis after myocardial infarction via targeting miR-144-3p

X Gong, Y Zhu, H Chang, Y Li, F Ma - bioscience reports, 2019 - portlandpress.com
Our study aims to excavate the role of metastasis-associated lung adenocarcinoma
transcript 1 (MALAT1) in myocardial infarction (MI), especially in an ischemia/reperfusion …

MALAT1 lncRNA induces autophagy and protects brain microvascular endothelial cells against oxygen–glucose deprivation by binding to miR-200c-3p and …

S Wang, X Han, Z Mao, Y Xin, S Maharjan, B Zhang - Neuroscience, 2019 - Elsevier
There is growing evidence that long noncoding RNAs (lncRNAs) play important roles in
various biological processes. Metastasis-associated lung adenocarcinoma transcript 1 …

[HTML][HTML] The lncRNA Malat1 regulates microvascular function after myocardial infarction in mice via miR-26b-5p/Mfn1 axis-mediated mitochondrial dynamics

Y Chen, S Li, Y Zhang, M Wang, X Li, S Liu, D Xu… - Redox Biology, 2021 - Elsevier
Rationale Myocardial infarction (MI) is a leading cause of cardiovascular mortality globally.
The improvement of microvascular function is critical for cardiac repair after MI. Evidence …

Modulation of the proliferation/apoptosis balance of vascular smooth muscle cells in atherosclerosis by lncRNA-MEG3 via regulation of miR-26a/Smad1 axis

Y Bai, Q Zhang, Y Su, Z Pu, K Li - International Heart Journal, 2019 - jstage.jst.go.jp
The balance between proliferation and apoptosis of vascular smooth muscle cells (VSMCs)
plays a critical role in the initiation of atherosclerosis. LncRNA-MEG3 is involved in the …

[HTML][HTML] MIAT promotes proliferation and hinders apoptosis by modulating miR-181b/STAT3 axis in ox-LDL-induced atherosclerosis cell models

X Zhong, X Ma, L Zhang, Y Li, Y Li, R He - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Background Plenty of lncRNAs and microRNAs have been identified to be critical mediators
in the progression of atherosclerosis (AS). Myocardial infarction-associated transcript (MIAT) …

[PDF][PDF] Long non-coding RNA MALAT1 regulates proliferation, apoptosis, migration and invasion via miR-374b-5p/SRSF7 axis in non-small cell lung cancer.

J Song, ZZ Su, QM Shen - European Review for Medical & …, 2020 - europeanreview.org
OBJECTIVE: Non-small cell lung cancer (NSCLC) is a common type of lung cancer. Long
noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 …