[HTML][HTML] The diverse mechanisms and anticancer potential of naphthoquinones

CE Pereyra, RF Dantas, SB Ferreira, LP Gomes… - Cancer Cell …, 2019 - Springer
Cancer is one of the leading causes of death around the world and although the different
clinical approaches have helped to increase survival rates, incidence is still high and so its …

Understanding cancer and the anticancer activities of naphthoquinones–a review

KW Wellington - RSC advances, 2015 - pubs.rsc.org
The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …

Naphthoquinones: A continuing source for discovery of therapeutic antineoplastic agents

HY Qiu, PF Wang, HY Lin, CY Tang… - Chemical biology & …, 2018 - Wiley Online Library
Naturally occurring naphthoquinones, usually in forms of botanical extracts, have been
implicated with human life since ancient time, far earlier than their isolation and identification …

Naphthoquinones and derivatives as potential anticancer agents: An updated review

MM Rahman, MR Islam, S Akash, S Shohag… - Chemico-Biological …, 2022 - Elsevier
One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …

Recent development on naphthoquinone derivatives and their therapeutic applications as anticancer agents

VK Tandon, S Kumar - Expert Opinion on Therapeutic Patents, 2013 - Taylor & Francis
Introduction: A large number of natural products including several synthetic drugs possess
naphthoquinone chromophore. Various methods have been devised for their synthesis …

Synthesis and anticancer evaluation of 1, 4‐naphthoquinone derivatives containing a phenylaminosulfanyl moiety

P Ravichandiran, SA Subramaniyan, SY Kim… - …, 2019 - Wiley Online Library
Naphthoquinones are exceptional building blocks in organic synthesis and have been used
to synthesize several well‐known pharmaceutically active agents. Herein we report the …

Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line

E Pérez-Sacau, RG Díaz-Peñate… - Journal of medicinal …, 2007 - ACS Publications
Catalyst/HypoGen pharmacophore modeling approach and three-dimensional quantitative
structure− activity relationship (3D-QSAR)/comparative molecular similarity indices analysis …

Recent studies on natural products as anticancer agents

AG Ravelo, A Estévez-Braun… - Current topics in …, 2004 - ingentaconnect.com
Cancer will be the major cause of death in the 21st century and natural products should
provide novel and more effective anticancer agents. This review deals with new natural …

Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents

J Benites, JA Valderrama, K Bettega… - European journal of …, 2010 - Elsevier
Several members of the phenylamino-1, 4-naphthoquinone series were prepared in order to
investigate structure–activity relationships (SAR) and to explore the antitumor effects …

[HTML][HTML] Naphthoquinones and their derivatives: emerging trends in combating microbial pathogens

NS Mone, SA Bhagwat, D Sharma, M Chaskar… - Coatings, 2021 - mdpi.com
In the current era, an ever-emerging threat of multidrug-resistant (MDR) pathogens pose
serious health challenges to mankind. Researchers are uninterruptedly putting their efforts …