Interaction between a polymorphism of the apo AI promoter region and smoking determines plasma levels of HDL and apo AI.

G Sigurdsson Jr, V Gudnason… - … and Thrombosis: A …, 1992 - Am Heart Assoc
Epidemiological studies have demonstrated that the risk of coronary artery disease (CAD) is
increased in smokers but reduced in individuals with elevated plasma levels of high density …

Polymorphism in the promoter region of the apolipoprotein AI gene associated with differences in apolipoprotein AI levels: the European Atherosclerosis Research …

PJ Talmud, S Ye, SE Humphries… - Genetic …, 1994 - Wiley Online Library
The effect associated with the substitution of adenine (A) for guanidine (G) in the promoter
region of the apolipoprotein AI gene (− 75 bp) with plasma apo AI and high‐density …

Polymorphisms at the 5'-end of the apolipoprotein AI gene and severity of coronary artery disease.

XL Wang, SX Liu, RM McCredie… - The Journal of clinical …, 1996 - Am Soc Clin Investig
Elevated HDL-cholesterol (C) and apo AI are associated with decreased coronary artery
disease (CAD) risk. We determined distributions of two MspI polymorphisms of the apo AI …

G→ A substitution at position− 75 of the apolipoprotein AI gene promoter: evidence against a direct effect on HDL cholesterol levels

A Minnich, G DeLangavant, J Lavigne… - … , and vascular biology, 1995 - Am Heart Assoc
The present study sought to resolve the contradictory evidence as to whether the G→ A
substitution at position− 75 of the apoA-I gene promoter raises HDL cholesterol (HDL-C) …

Genetic analysis of a polymorphism in the human apolipoprotein AI gene promoter: effect on plasma HDL-cholesterol levels.

DE Barre, R Guerra, R Verstraete, Z Wang… - Journal of lipid …, 1994 - Elsevier
Previous studies have indicated that a G to A substitution at position-76 in the gene
encoding apolipoprotein AI (apoA-I) confers increased plasma high density lipoprotein …

G to A substitution in the promoter region of the apolipoprotein AI gene is associated with elevated serum apolipoprotein AI and high density lipoprotein cholesterol …

M Jeenah, A Kessling, N Miller… - Molecular biology & …, 1990 - europepmc.org
We have determined the sequence of 250 bases 5'of the transcriptional start site of the
apolipoprotein AI gene in a human individual with high serum concentrations of apo AI. One …

Apolipoprotein AI gene polymorphisms: frequency in patients with coronary artery disease and healthy controls and association with serum apo AI and HDL …

DB Wile, M Barbir, J GallagherP, NB Myant, CD Ritchie… - Atherosclerosis, 1989 - Elsevier
We have investigated the association between serum high density lipoprotein-cholesterol
(HDL-C) and apo AI concentration and the Pstl and XmnI restriction fragment length …

Guanidine to adenine (G/A) substitution in the promoter region of the apolipoprotein AI gene is associated with elevated serum apolipoprotein AI levels in Chinese non …

N Saha, JSH Tay, PS Low… - Genetic …, 1994 - Wiley Online Library
The influence of the guanidine to adenine (G/A) substitution in the promoter region of the
apolipoprotein (apo) AI gene (at− 75 bp) on serum lipids and apolipoproteins was studied in …

Apo AI promoter polymorphism influences basal HDL-cholesterol and its response to pravastatin therapy

C Lahoz, R Peña, JM Mostaza, J Jiménez, E Subirats… - Atherosclerosis, 2003 - Elsevier
Statins decrease cardiovascular morbidity and mortality, essentially, by reducing LDL-
cholesterol levels and, additionally, by increasing HDL-cholesterol concentrations …

Human apolipoprotein AI gene promoter polymorphism: association with hyperalphalipoproteinemia.

F Pagani, A Sidoli, GA Giudici, L Barenghi… - Journal of Lipid …, 1990 - ASBMB
An apolipoprotein AI gene promoter polymorphism, due to an adenine (A) to guanine (G)
transition 78 base pairs upstream from the transcription initiation site, was studied by …