This contribution describes the current state of experimental model development and use as
a strategy for gaining insight into the form and function of certain types of host-microbe …

Current work in experimental biology revolves around a handful of animal species. Studying
only a few organisms limits science to the answers that those organisms can provide. Nature …

Symbiotic associations involving prokaryotes occur ubiquitously and are ecologically highly
significant. In symbiotic associations, co-evolution of the partner organisms has led to …

Animals are symbiotic superorganisms, composed of eukaryotic cells and specific microbial
residents that perform essential functions for their host. As humans, we are beginning to …

Microorganisms play a significant role in the evolution and functioning of the eukaryotes with
which they interact. Much of our understanding of beneficial host–microbe interactions stems …

Beneficial associations with bacteria are widespread across animals, spanning a range of
symbiont localizations, transmission routes, and functions. While some of these associations …

The recent development and application of molecular genetics to the symbionts of
invertebrate animal species have advanced our knowledge of the biochemical …

For the first billion years of life on Earth, prokaryotes had the place to themselves. By the
time the first eukaryotes and then, finally, multicellular organisms arose and diversified …

The study of symbiosis is quintessential systems biology. It integrates not only all levels of
biological analysis—from molecular to ecological—but also the study of the interplay …

Microbial symbionts are ubiquitous and can have significant impact on hosts. These impacts
can vary in the sign (positive or negative) and degree depending on the identity of the …