Coagulopathy in isolated traumatic brain injury: myth or reality

R Mathur, JI Suarez - Neurocritical care, 2023 - Springer
Abstract Introduction Traumatic Brain Injury (TBI) has been shown to be associated with
altered hemostasis and coagulopathy, that correlates with worsening secondary injury and …

Coagulopathy and progression of intracranial hemorrhage in traumatic brain injury: mechanisms, impact, and therapeutic considerations

M Maegele - Neurosurgery, 2021 - journals.lww.com
BACKGROUND Traumatic brain injury (TBI) remains one of the most challenging health and
socioeconomic problems of our times. Clinical courses may be complicated by hemostatic …

Coagulation disorders after traumatic brain injury

BS Harhangi, EJO Kompanje, FWG Leebeek… - Acta …, 2008 - Springer
Background. Over the past decade new insights in our understanding of coagulation have
identified the prominent role of tissue factor. The brain is rich in tissue factor, and injury to the …

Multicenter evaluation of the course of coagulopathy in patients with isolated traumatic brain injury: relation to CT characteristics and outcome

G Franschman, C Boer, TMJC Andriessen… - Journal of …, 2012 - liebertpub.com
This prospective multicenter study investigated the association of the course of coagulation
abnormalities with initial computed tomography (CT) characteristics and outcome in patients …

Coagulopathy after traumatic brain injury: incidence, pathogenesis, and treatment options

M Maegele - Transfusion, 2013 - Wiley Online Library
Coagulopathy after traumatic brain injury (TBI) is frequent and represents a powerful
predictor related to outcome and prognosis. The complex pathophysiological mechanisms of …

Coagulopathy in traumatic brain injury and its correlation with progressive hemorrhagic injury: a systematic review and meta-analysis

Q Yuan, Y Sun, X Wu, J Yu, Z Li, Z Du, X Wu… - Journal of …, 2016 - liebertpub.com
The association between coagulopathy and either isolated traumatic brain injury (TBI) or
progressive hemorrhagic injury (PHI) remains controversial. The aims of this study were to …

Coagulopathy as prognostic marker in acute traumatic brain injury

G Chhabra, S Sharma, A Subramanian… - … , trauma, and shock, 2013 - journals.lww.com
Aims: To assess the incidence and probable risk factors for development of coagulopathy
and to identify the risk factors for poor outcome in terms of median survival time following …

Global characterisation of coagulopathy in isolated traumatic brain injury (iTBI): a CENTER-TBI analysis

JK Böhm, H Güting, S Thorn, N Schäfer, V Rambach… - Neurocritical care, 2021 - Springer
Background Trauma-induced coagulopathy in patients with traumatic brain injury (TBI) is
associated with high rates of complications, unfavourable outcomes and mortality. The …

Coagulopathy induced by traumatic brain injury: systemic manifestation of a localized injury

J Zhang, F Zhang, J Dong - Blood, The Journal of the American …, 2018 - ashpublications.org
Traumatic brain injury (TBI)–induced coagulopathy is a common and well-recognized risk for
poor clinical outcomes, but its pathogenesis remains poorly understood, and treatment …

Traumatic brain injury associated coagulopathy

AL de Oliveira Manoel, AC Neto, PV Veigas, S Rizoli - Neurocritical care, 2015 - Springer
Background The presence of coagulopathy is common after severe trauma. The aim of this
study was to identify whether isolated severe traumatic brain injury (TBI) is an independent …