[HTML][HTML] Podoplanin in inflammation and cancer

M Quintanilla, L Montero-Montero, J Renart… - International journal of …, 2019 - mdpi.com
Podoplanin is a small cell-surface mucin-like glycoprotein that plays a crucial role in the
development of the alveoli, heart, and lymphatic vascular system. Emerging evidence …

[HTML][HTML] Roles of podoplanin in malignant progression of tumor

H Suzuki, MK Kaneko, Y Kato - Cells, 2022 - mdpi.com
Podoplanin (PDPN) is a cell-surface mucin-like glycoprotein that plays a critical role in tumor
development and normal development of the lung, kidney, and lymphatic vascular systems …

Podoplanin: a novel regulator of tumor invasion and metastasis

Q Dang, J Liu, J Li, Y Sun - Medical oncology, 2014 - Springer
Podoplanin, a small mucin-type sialoglycoprotein, was recently shown to be involved in
tumor progression. Podoplanin is overexpressed in cancer cells of various human …

New insights into the role of podoplanin in epithelial–mesenchymal transition

J Renart, P Carrasco-Ramírez… - International review of …, 2015 - Elsevier
Podoplanin is a small mucin-like transmembrane protein expressed in several adult tissues
and with an important role during embryogenesis. It is needed for the proper development of …

[HTML][HTML] Podoplanin: emerging functions in development, the immune system, and cancer

JL Astarita, SE Acton, SJ Turley - Frontiers in immunology, 2012 - frontiersin.org
Podoplanin (PDPN) is a well-conserved, mucin-type transmembrane protein expressed in
multiple tissues during ontogeny and in adult animals, including the brain, heart, kidney …

[HTML][HTML] Significance of podoplanin expression in cancer-associated fibroblasts: a comprehensive review

B Pula, W Witkiewicz, P Dziegiel… - International …, 2013 - spandidos-publications.com
Cancer-associated fibroblasts (CAFs) are well-known to be part of the tumor
microenvironment. This heterogeneous population of cells of the tumor microenvironment …

Podoplanin: an emerging cancer biomarker and therapeutic target

H Krishnan, J Rayes, T Miyashita, G Ishii… - Cancer …, 2018 - Wiley Online Library
Podoplanin (PDPN) is a transmembrane receptor glycoprotein that is upregulated on
transformed cells, cancer associated fibroblasts and inflammatory macrophages that …

[HTML][HTML] Podoplanin-a small glycoprotein with many faces

M Ugorski, P Dziegiel, J Suchanski - American journal of cancer …, 2016 - ncbi.nlm.nih.gov
Podoplanin is a small membrane glycoprotein with a large number of O-glycoside chains
and therefore it belongs to mucin-type proteins. It can be found on the surface of many types …

The role of podoplanin in tumor progression and metastasis

M Raica, AM Cimpean, D Ribatti - Anticancer research, 2008 - ar.iiarjournals.org
In the last decade, much data has been generated concerning the molecular mechanisms of
lymphangiogenesis and its significance in pathological conditions. This was mainly due to …

Overexpression of podoplanin in oral cancer and its association with poor clinical outcome

P Yuan, S Temam, A El‐Naggar, X Zhou, DD Liu… - Cancer, 2006 - Wiley Online Library
BACKGROUND. Podoplanin is a mucin‐like glycoprotein that is important in
lymphangiogenesis but not blood vessel formation. Recent studies suggested a potential …